EPHX1, epoxide hydrolase 1, 2052

N. diseases: 196; N. variants: 5
Disease: Esophageal Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE The association between the EPHX1 Tyr113His and His139Arg</span> polymorphisms and EC risk was pooled by odds ratios (ORs) together with their 95% confidence intervals (95%CIs). 25714851 2015
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE However, no evidence was found for the association between the EPHX1 Hi</span>s139Arg polymorphism and esophageal cancer risk. 24615030 2014
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE This meta-analysis suggests that the p.Tyr113His and p.His139Arg polymorphisms in EPHX1 may not be associated with EC development. 24803829 2014
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE Meta-analysis of these seven studies for EPHX1 H</span>is139Arg polymorphism showed that EPHX1 His139Arg polymorphism was also not associated with esophageal cancer</span> risk under all genetic models. 23681797 2013
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE No significant association was found in either the allele or genotype models for Tyr113His or His1</span>39Arg polymorphism with risk for esophageal cancer</span>. 24222229 2013
dbSNP: rs2234922
rs2234922
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1
CUI: C0014859
Disease:
Esophageal Neoplasms 		0.060 GeneticVariation BEFREE EPHX1 exon 4 139His/Arg, and 139Arg/Arg genotypes were associated with a higher risk of esophageal cancer in a high-risk area of India. 20659238 2010