ERBB4, erb-b2 receptor tyrosine kinase 4, 2066

N. diseases: 317; N. variants: 75
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs397514262
rs397514262
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C3715155
Disease:
AMYOTROPHIC LATERAL SCLEROSIS 19 		T 0.800 CausalMutation CLINVAR
dbSNP: rs397514263
rs397514263
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C3715155
Disease:
AMYOTROPHIC LATERAL SCLEROSIS 19 		A 0.800 CausalMutation CLINVAR
dbSNP: rs7558615
rs7558615
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7558615
rs7558615
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7558615
rs7558615
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7558615
rs7558615
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs7564590
rs7564590
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006826
Disease:
Malignant Neoplasms 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0600139
Disease:
Prostate carcinoma 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0376358
Disease:
Malignant neoplasm of prostate 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0678222
Disease:
Breast Carcinoma 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs905883
rs905883
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.010 GeneticVariation BEFREE In analysis of selected candidate cancer susceptibility genes, two MSR1 SNPs (rs9325782, GEE p = 0.008 and rs2410373, FBAT p = 0.021) were associated with prostate cancer and three ERBB4 SNPs (rs905883 GEE p = 0.0002, rs7564590 GEE p = 0.003, rs7558615 GEE p = 0.0078) were associated with breast cancer. 17903305 2007
dbSNP: rs202247795
rs202247795
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		T 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs267599192
rs267599192
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		A 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs267599193
rs267599193
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		T 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs535202189
rs535202189
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		T 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs55671017
rs55671017
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		A 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs776347334
rs776347334
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0025202
Disease:
melanoma 		T 0.700 GeneticVariation CLINVAR Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4. 19718025 2009
dbSNP: rs3748962
rs3748962
Entrez Id: 2066
Gene Symbol: ERBB4
ERBB4
CUI: C0036341
Disease:
Schizophrenia 		0.020 GeneticVariation BEFREE In comparison with subjects of the rs3748962-TT type, those of the rs3748962-CT and rs3748962-CC types were at 1.74- and 2.64-fold greater risk of s</span>chizophrenia (CT vs. TT: OR=1.71 (95% CI=1.15-2.53), p=0.0014; CC vs. TT: OR=2.64 (95% CI=1.37-5.23), p=0.0047), which supports the hypothesis of an additive model of transmission (p=0.0006). 20600594 2010