rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
A
0.810
GeneticVariation
GWASCAT
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
26908601
2016
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
A
0.810
SusceptibilityMutation
CLINVAR
Prevalence and Geographical Variation of Prothrombin G20210A Mutation in Patients with Cerebral Vein Thrombosis: A Systematic Review and Meta-Analysis.
27031503
2016
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
0.810
GeneticVariation
BEFREE
In multinomial multivariate adjusted analysis, rs1799963 was exclusively associated with undetermined stroke (OR: 3.67; 95% CI: 1.52-8.85; p = 0.004).
25897999
2015
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
A
0.810
SusceptibilityMutation
CLINVAR
The genetics of venous thromboembolism. A meta-analysis involving approximately 120,000 cases and 180,000 controls.
19652888
2009
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
A
0.810
SusceptibilityMutation
CLINVAR
The prothrombin 3'end formation signal reveals a unique architecture that is sensitive to thrombophilic gain-of-function mutations.
15059842
2004
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Cerebrovascular accident
A
0.810
SusceptibilityMutation
CLINVAR
Increased efficiency of mRNA 3' end formation: a new genetic mechanism contributing to hereditary thrombophilia.
11443298
2001
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
T
0.800
GeneticVariation
GWASCAT
Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids.
30926973
2019
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
T
0.800
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
C
0.800
GeneticVariation
GWASCAT
Discovery and refinement of loci associated with lipid levels.
24097068
2013
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
C
0.800
GeneticVariation
GWASDB
Discovery and refinement of loci associated with lipid levels.
24097068
2013
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
C
0.800
GeneticVariation
GWASCAT
Biological, clinical and population relevance of 95 loci for blood lipids.
20686565
2010
rs3136441
×
Entrez Id:
2147
Gene Symbol:
F2
F2
High density lipoprotein measurement
C
0.800
GeneticVariation
GWASDB
Biological, clinical and population relevance of 95 loci for blood lipids.
20686565
2010
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
0.730
GeneticVariation
BEFREE
Our findings suggest that the risk of VTE by FHMI is not explained by rs8176719 (ABO), rs6025 (F5), rs1799963 (F2), rs2066865 (FGG), and rs2036914 (F11).
31124268
2019
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
A
0.730
GeneticVariation
GWASCAT
Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.
31676865
2019
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
0.730
GeneticVariation
GWASCAT
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
31420334
2019
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
A
0.730
GeneticVariation
GWASCAT
Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor.
28373160
2017
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
A
0.730
GeneticVariation
GWASCAT
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
26908601
2016
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
A
0.730
GeneticVariation
GWASCAT
Meta-analysis of 65,734 individuals identifies TSPAN15 and SLC44A2 as two susceptibility loci for venous thromboembolism.
25772935
2015
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
0.730
GeneticVariation
BEFREE
Factor V Leiden (FVL or rs6025) and prothrombin gene G20210A (PT or rs1799963 ) are the genetic variants currently tested for VTE risk assessment.
25341889
2014
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
0.730
GeneticVariation
BEFREE
Apart from F5 rs6025, ABO rs8176719, rs2519093 and F2 rs1799963 , additional common and high VTE -risk SNPs among whites are unlikely.
22672568
2012
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Ischemic stroke
0.720
GeneticVariation
BEFREE
A total of nine gene variants/polymorphisms - F5 (Leiden - R5 06Q, rs6025), F2 (20210G > A, rs1799963 ), F13A1 (V34L, rs5985), MTHFR (677C > T - A222V, rs1801133), MTHFR (1298A > C - E429A, rs1801131), FGB (-455G > A -c.-463G > A; rs1800790), SERPINE1 (PAI14G/5G - rs1799889), ACE (ACE I/D, rs1799752), ITGB3 (GPIIIa L33P, rs5918) and the APOE E2/E3/E4 alleles (rs7412, rs429358) - were genotyped in 200 newly diagnosed ischemic stroke (IS) patients, 165 patients with ischemic coronary heart disease (CHD) and 159 controls with no cerebroor cardiovascular disease (non-CVD).
27629735
2016
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Ischemic stroke
A
0.720
GeneticVariation
GWASCAT
Genome-wide association analysis of self-reported events in 6135 individuals and 252 827 controls identifies 8 loci associated with thrombosis.
26908601
2016
rs1799963
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Ischemic stroke
0.720
GeneticVariation
BEFREE
We evaluated the differences in the distribution of rs6025 and rs1799963 polymorphisms according to IS subtypes and their interaction with smoking.
25897999
2015
rs3136516
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Venous Thromboembolism
G
0.700
GeneticVariation
GWASCAT
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism.
31420334
2019
rs776618390
×
Entrez Id:
2147
Gene Symbol:
F2
F2
Reduced prothrombin activity
C
0.700
GeneticVariation
CLINVAR
Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.
31064749
2019