FGB, fibrinogen beta chain, 2244

N. diseases: 95; N. variants: 30
Disease: Cardioembolism (high-risk/medium-risk) ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1800790
rs1800790
Entrez Id: 2244
Gene Symbol: FGB
FGB
CUI: C4699508
Disease:
Cardioembolism (high-risk/medium-risk) 		0.010 GeneticVariation BEFREE After stratifying IS by three common subtypes, consistent results were found in IS cases with large-artery atherosclerosis (rs6050: OR=2.116, 95% CI: 1.327-3.376, p=0.002; rs1800790: OR=0.191, 95% CI: 0.085-0.430, p=0.000), and we also observed that the homozygous minor allele genotype of rs6050 increased risk by 86% in IS cases with cardioembolism (OR=1.859, 95% CI: 1.243-2.782, p=0.003). 23944290 2013