Variant Gene Disease Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2981578
rs2981578
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.040 GeneticVariation BEFREE Thus, the apparent increased risk of developing ERα positive breast cancer seems not to be caused by rs2981578 alone. 24265722 2014
dbSNP: rs2981578
rs2981578
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.040 GeneticVariation BEFREE Results from the current meta-analysis indicates that three novel functional polymorphisms (rs11200014, rs2981579, and rs2981578) in the promoter of FGFR2 gene are associated with breast cancer susceptibility and might be a potential biomarkers for breast cancer risk. 23124475 2013
dbSNP: rs2981578
rs2981578
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.040 GeneticVariation BEFREE Our results suggest that the increased breast cancer risk associated with SNP rs2981578 is due to increased FGFR2 signaling activity in stromal fibroblasts, possibly also involving paracrine FGF10 signaling. 21767389 2012
dbSNP: rs2981578
rs2981578
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.040 GeneticVariation BEFREE A significant association with BC risk was found with SNP rs2981578 (unadjusted per-allele odds ratio = 1.20, 95% confidence interval 1.03-1.41, P(trend) = 0.02), with the odds ratio estimate similar to that reported in European and Asian subjects. 19223389 2009