Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11130760
rs11130760
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0220641
Disease:
Lip and Oral Cavity Carcinoma
T 0.710 GeneticVariation CLINVAR The SNP rs11130760 wild-type (WT) allele G indicated an increased risk for oral cancer (OR 1.38; 95% CI 1.09-1.73), whereas SNP allele T indicated a decreased risk (OR 0.73; 95% CI 0.58-0.92) for oral cancer. 28580594 2017
dbSNP: rs11130760
rs11130760
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0220641
Disease:
Lip and Oral Cavity Carcinoma
0.710 GeneticVariation BEFREE The SNP rs11130760 wild-type (WT) allele G indicated an increased risk for oral cancer (OR 1.38; 95% CI 1.09-1.73), whereas SNP allele T indicated a decreased risk (OR 0.73; 95% CI 0.58-0.92) for oral cancer. 28580594 2017
dbSNP: rs139239158
rs139239158
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0600139
Disease:
Prostate carcinoma
0.700 GeneticVariation GWASCAT Radiogenomics Consortium Genome-Wide Association Study Meta-Analysis of Late Toxicity After Prostate Cancer Radiotherapy. 31095341 2020
dbSNP: rs1353545
rs1353545
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0036341
Disease:
Schizophrenia
C 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260 2019
dbSNP: rs141954845
rs141954845
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1269683
Disease:
Major Depressive Disorder
A 0.700 GeneticVariation GWASCAT Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions. 30718901 2019
dbSNP: rs1916801
rs1916801
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1305855
Disease:
Body mass index
A 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. 30239722 2019
dbSNP: rs1966136
rs1966136
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1269683
Disease:
Major Depressive Disorder
A 0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913 2019
dbSNP: rs1966136
rs1966136
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0036341
Disease:
Schizophrenia
A 0.700 GeneticVariation GWASCAT Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression. 30626913 2019
dbSNP: rs2366964
rs2366964
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C4721579
Disease:
Secondary malignant neoplasm of colon and/or rectum
C 0.700 GeneticVariation GWASCAT A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer. 30738427 2019
dbSNP: rs3915074
rs3915074
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0424678
Disease:
Lean body mass
0.700 GeneticVariation GWASCAT Genomics of body fat percentage may contribute to sex bias in anorexia nervosa. 30593698 2019
dbSNP: rs11920657
rs11920657
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0410702
Disease:
Adolescent idiopathic scoliosis
0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs11920657
rs11920657
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1837461
Disease:
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
0.700 GeneticVariation GWASCAT The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease. 30019117 2018
dbSNP: rs11922368
rs11922368
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C2985280
Disease:
Blood Protein Measurement
C 0.700 GeneticVariation GWASCAT Co-regulatory networks of human serum proteins link genetics to disease. 30072576 2018
dbSNP: rs1554600
rs1554600
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0007766
Disease:
Intracranial Aneurysm
0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies new candidate risk loci for familial intracranial aneurysm in the French-Canadian population. 29531279 2018
dbSNP: rs2365389
rs2365389
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1305855
Disease:
Body mass index
C 0.700 GeneticVariation GWASCAT A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci. 30108127 2018
dbSNP: rs10222378
rs10222378
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
A 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs13061562
rs13061562
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute
T 0.700 GeneticVariation GWASCAT Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia. 27903959 2017
dbSNP: rs1353545
rs1353545
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0036341
Disease:
Schizophrenia
C 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026 2017
dbSNP: rs1353545
rs1353545
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0008074
Disease:
Child Development Disorders, Pervasive
C 0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026 2017
dbSNP: rs1353545
rs1353545
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0036341
Disease:
Schizophrenia
C 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256 2017
dbSNP: rs138741635
rs138741635
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0948089
Disease:
Acute Coronary Syndrome
A 0.700 GeneticVariation GWASCAT Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib. 28753643 2017
dbSNP: rs138741635
rs138741635
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0010068
Disease:
Coronary heart disease
A 0.700 GeneticVariation GWASCAT Pharmacogenetic meta-analysis of baseline risk factors, pharmacodynamic, efficacy and tolerability endpoints from two large global cardiovascular outcomes trials for darapladib. 28753643 2017
dbSNP: rs1916799
rs1916799
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C1305855
Disease:
Body mass index
A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs1916799
rs1916799
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0005910
Disease:
Body Weight
A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017
dbSNP: rs1916799
rs1916799
Entrez Id: 2272
Gene Symbol: FHIT
FHIT
CUI: C0455829
Disease:
Waist Circumference
A 0.700 GeneticVariation GWASCAT Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. 28552196 2017