rs7721607
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Adverse effects, not elsewhere classified
A
0.700
GeneticVariation
GWASCAT
Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records.
30420678
2019
rs80333777
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
response to simvastatin
0.700
GeneticVariation
GWASCAT
Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
28736931
2018
rs80333777
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Diabetes Mellitus, Non-Insulin-Dependent
0.700
GeneticVariation
GWASCAT
Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
28736931
2018
rs147776718
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
response to bronchodilator
A
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
26634245
2015
rs147776718
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Chronic Obstructive Airway Disease
A
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry.
26634245
2015
rs16867528
FBXL7;CTD-2350J17.1
Asthma
A
0.700
GeneticVariation
GWASCAT
Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.
25918132
2015
rs75002042
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Alzheimer's Disease
T
0.700
GeneticVariation
GWASCAT
F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease.
26339675
2015
rs76684306
FBXL7;CTD-2350J17.1
Asthma
G
0.700
GeneticVariation
GWASCAT
Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.
25918132
2015
rs10044254
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Asthma
0.700
GeneticVariation
GWASCAT
However, these 3 SNPs were not additionally replicated in the adult asthmatic patients of the remaining trials. rs10044254 lies in the intronic region of F-box and leucine-rich repeat protein 7 (FBXL7) and is associated with decreased expression in immortalized B cells derived from CAMP participants.
24486069
2014
rs12659622
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Polysomnography
A
0.700
GeneticVariation
GWASDB
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
23251661
2012
rs12659622
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Hormone measurement
A
0.700
GeneticVariation
GWASCAT
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
23251661
2012
rs983889
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Congenital chromosomal disease
0.010
GeneticVariation
BEFREE
Replication 1 supported the association of rs1383997 (8q13.3) and rs2824215 (21q21.1) in CAtot and rs983889 (5p15.1) in CTA analysis.
30368896
2019
rs10044254
×
Entrez Id:
23194
Gene Symbol:
FBXL7
FBXL7
Childhood asthma
0.010
GeneticVariation
BEFREE
Of the 60 SNPs available in the Childhood Asthma Research and Education Network trials, rs1558726 (combined P = 1.02 × 10(-5)), rs2388639 (combined P = 8.56 × 10(-9)), and rs10044254 (combined P = 9.16 × 10(-8)) independently replicated.
24486069
2014