Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7721607
rs7721607
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0869220
Disease:
Adverse effects, not elsewhere classified
A 0.700 GeneticVariation GWASCAT Genetic variation in the Estonian population: pharmacogenomics study of adverse drug effects using electronic health records. 30420678 2019
dbSNP: rs80333777
rs80333777
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C3894553
Disease:
response to simvastatin
0.700 GeneticVariation GWASCAT Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. 28736931 2018
dbSNP: rs80333777
rs80333777
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent
0.700 GeneticVariation GWASCAT Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes. 28736931 2018
dbSNP: rs147776718
rs147776718
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C3548479
Disease:
response to bronchodilator
A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs147776718
rs147776718
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease
A 0.700 GeneticVariation GWASCAT A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. 26634245 2015
dbSNP: rs16867528
rs16867528
Entrez Id: 23194;101929472
Gene Symbol: FBXL7;CTD-2350J17.1
FBXL7;CTD-2350J17.1
CUI: C0004096
Disease:
Asthma
A 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma. 25918132 2015
dbSNP: rs75002042
rs75002042
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0002395
Disease:
Alzheimer's Disease
T 0.700 GeneticVariation GWASCAT F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease. 26339675 2015
dbSNP: rs76684306
rs76684306
Entrez Id: 23194;101929472
Gene Symbol: FBXL7;CTD-2350J17.1
FBXL7;CTD-2350J17.1
CUI: C0004096
Disease:
Asthma
G 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma. 25918132 2015
dbSNP: rs10044254
rs10044254
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0004096
Disease:
Asthma
0.700 GeneticVariation GWASCAT However, these 3 SNPs were not additionally replicated in the adult asthmatic patients of the remaining trials. rs10044254 lies in the intronic region of F-box and leucine-rich repeat protein 7 (FBXL7) and is associated with decreased expression in immortalized B cells derived from CAMP participants. 24486069 2014
dbSNP: rs12659622
rs12659622
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0162701
Disease:
Polysomnography
A 0.700 GeneticVariation GWASDB Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. 23251661 2012
dbSNP: rs12659622
rs12659622
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0441683
Disease:
Hormone measurement
A 0.700 GeneticVariation GWASCAT Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. 23251661 2012
dbSNP: rs983889
rs983889
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0008626
Disease:
Congenital chromosomal disease
0.010 GeneticVariation BEFREE Replication 1 supported the association of rs1383997 (8q13.3) and rs2824215 (21q21.1) in CAtot and rs983889 (5p15.1) in CTA analysis. 30368896 2019
dbSNP: rs10044254
rs10044254
Entrez Id: 23194
Gene Symbol: FBXL7
FBXL7
CUI: C0264408
Disease:
Childhood asthma
0.010 GeneticVariation BEFREE Of the 60 SNPs available in the Childhood Asthma Research and Education Network trials, rs1558726 (combined P = 1.02 × 10(-5)), rs2388639 (combined P = 8.56 × 10(-9)), and rs10044254 (combined P = 9.16 × 10(-8)) independently replicated. 24486069 2014