rs11842874
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Degenerative polyarthritis
0.810
GeneticVariation
BEFREE
One of the reported OA association signals is marked by the single nucleotide polymorphism (SNP) rs11842874 at chromosome 13q34. rs11842874 is positioned within a small linkage disequilibrium (LD) block within intron 4 of MCF2L, a gene encoding guanine-nucleotide exchange factor DBS.
26584642
2015
rs11842874
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Degenerative polyarthritis
A
0.810
GeneticVariation
GWASCAT
Through large-scale replication, we establish a robust association with SNPs in MCF2L (rs11842874 , combined odds ratio [95% confidence interval] 1.17 [1.11-1.23], p = 2.1 × 10(-8)) across a total of 19,041 OA cases and 24,504 controls of European descent.
21871595
2011
rs11842874
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Degenerative polyarthritis
A
0.810
GeneticVariation
GWASDB
Through large-scale replication, we establish a robust association with SNPs in MCF2L (rs11842874 , combined odds ratio [95% confidence interval] 1.17 [1.11-1.23], p = 2.1 × 10(-8)) across a total of 19,041 OA cases and 24,504 controls of European descent.
21871595
2011
rs1046205
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Factor VII measurement
A
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
30642921
2019
rs10665
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
A
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs10665
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Coagulation factor measurement
A
0.700
GeneticVariation
GWASCAT
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs117989138
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Factor VII measurement
A
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
30642921
2019
rs1317507
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Coronary Artery Disease
A
0.700
GeneticVariation
GWASCAT
Identification of 64 Novel Genetic Loci Provides an Expanded View on the Genetic Architecture of Coronary Artery Disease.
29212778
2018
rs2146751
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs2146752
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs2181540
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Coagulation factor measurement
T
0.700
GeneticVariation
GWASCAT
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs2181540
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
T
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs2476325
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs2480952
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Factor VII measurement
T
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
30642921
2019
rs2873281
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs3011549
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Systolic Pressure
A
0.700
GeneticVariation
GWASCAT
Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.
27841878
2017
rs36086577
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Factor VII measurement
C
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
30642921
2019
rs521720
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs534298
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs553702
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs71446935
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Factor VII measurement
A
0.700
GeneticVariation
GWASCAT
A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology.
30642921
2019
rs7327099
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs9324220
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
von Willebrand's factor (lab test)
0.700
GeneticVariation
GWASDB
Ischemic stroke is associated with the ABO locus: the EuroCLOT study.
23381943
2013
rs9549328
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Systolic Pressure
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019
rs9549328
×
Entrez Id:
23263
Gene Symbol:
MCF2L
MCF2L
Cardiovascular Diseases
0.700
GeneticVariation
GWASCAT
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
30595370
2019