SIRT1, sirtuin 1, 23411

N. diseases: 675; N. variants: 21
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3758391
rs3758391
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE The polymorphisms rs3758391 and rs1800470 located in SIRT1 and TGF-β1 have been associated with type 2 diabetes in different populations but its functional effect is not clear. 31799723 2020
dbSNP: rs3758391
rs3758391
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE We failed to find any significant association between rs3758391 polymorphisms and T2DM, DF susceptibility. 29995800 2018
dbSNP: rs3758391
rs3758391
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.030 GeneticVariation BEFREE Nominally significant associations were also observed between T2D and the SIRT1 rs3758391 SNP and MS and the HHEX rs5015480 polymorphism. 20503258 2010