FPR1, formyl peptide receptor 1, 2357

N. diseases: 93; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs112591851
rs112591851
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0003467
Disease:
Anxiety
T 0.700 GeneticVariation GWASCAT Meta-analysis of genome-wide association studies for neuroticism in 449,484 individuals identifies novel genetic loci and pathways. 29942085 2018
dbSNP: rs74256604
rs74256604
Entrez Id: 2357;2359
Gene Symbol: FPR1;FPR3
FPR1;FPR3
CUI: C0392885
Disease:
High density lipoprotein measurement
A 0.700 GeneticVariation GWASCAT Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program. 30275531 2018
dbSNP: rs5030879
rs5030879
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0031106
Disease:
Aggressive Periodontitis
0.020 GeneticVariation BEFREE Formylpeptide receptor single nucleotide polymorphism 348T>C and its relationship to polymorphonuclear leukocyte chemotaxis in aggressive periodontitis. 19722801 2009
dbSNP: rs5030879
rs5030879
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0001342
Disease:
Acute periodontitis
0.020 GeneticVariation BEFREE FPR1 SNP c.348T>C is associated with AgP in African Americans. 19254133 2009
dbSNP: rs5030879
rs5030879
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0001342
Disease:
Acute periodontitis
0.020 GeneticVariation BEFREE Formylpeptide receptor single nucleotide polymorphism 348T>C and its relationship to polymorphonuclear leukocyte chemotaxis in aggressive periodontitis. 19722801 2009
dbSNP: rs5030879
rs5030879
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0031106
Disease:
Aggressive Periodontitis
0.020 GeneticVariation BEFREE FPR1 SNP c.348T>C is associated with AgP in African Americans. 19254133 2009
dbSNP: rs11666254
rs11666254
Entrez Id: 2357;2358
Gene Symbol: FPR1;FPR2
FPR1;FPR2
CUI: C0036690
Disease:
Septicemia
0.010 GeneticVariation BEFREE The rs11666254 polymorphism in the FPR2/ALX gene is a functional SNP that increases sepsis susceptibility in patients after traumatic injury. 28679406 2017
dbSNP: rs11666254
rs11666254
Entrez Id: 2357;2358
Gene Symbol: FPR1;FPR2
FPR1;FPR2
CUI: C0243026
Disease:
Sepsis
0.010 GeneticVariation BEFREE The rs11666254 polymorphism in the FPR2/ALX gene is a functional SNP that increases sepsis susceptibility in patients after traumatic injury. 28679406 2017
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C1504336
Disease:
Polypoidal choroidal vasculopathy
0.010 GeneticVariation BEFREE Homozygous G allele of rs1042229 was associated with exudative AMD (P=0.0394, odds ratio (OR)=2.27, 95% confident interval: 1.08-4.74), but not with PCV. 25277308 2014
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0242383
Disease:
Age related macular degeneration
0.010 GeneticVariation BEFREE Homozygous G allele of rs1042229 was associated with exudative AMD (P=0.0394, odds ratio (OR)=2.27, 95% confident interval: 1.08-4.74), but not with PCV. 25277308 2014
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0017921
Disease:
Glycogen storage disease type II
0.010 GeneticVariation BEFREE Homozygous G allele of rs1042229 was associated with exudative AMD (P=0.0394, odds ratio (OR)=2.27, 95% confident interval: 1.08-4.74), but not with PCV. 25277308 2014
dbSNP: rs2070746
rs2070746
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C1504336
Disease:
Polypoidal choroidal vasculopathy
0.010 GeneticVariation BEFREE Exudative AMD, but not PCV, was associated with the heterozygous genotypes of rs2070746 (P=0.019, OR=0.57) and rs867229 (P=0.0082, OR=0.54). 25277308 2014
dbSNP: rs78488639
rs78488639
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0017921
Disease:
Glycogen storage disease type II
0.010 GeneticVariation BEFREE FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative AMD and PCV. 25277308 2014
dbSNP: rs78488639
rs78488639
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C1504336
Disease:
Polypoidal choroidal vasculopathy
0.010 GeneticVariation BEFREE FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative AMD and PCV. 25277308 2014
dbSNP: rs78488639
rs78488639
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0242383
Disease:
Age related macular degeneration
0.010 GeneticVariation BEFREE FPR1 rs78488639 interacted with CFH rs800292, HTRA1 rs11200638, and smoking, enhancing risk to exudative AMD and PCV. 25277308 2014
dbSNP: rs867229
rs867229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0242383
Disease:
Age related macular degeneration
0.010 GeneticVariation BEFREE Single nucleotide polymorphisms (SNP) rs78488639 increased the risk to exudative AMD (P=0.043) and PCV (P=0.016), whereas SNP rs867229 decreased the risk to exudative AMD (P=0.0026), but not PCV. 25277308 2014
dbSNP: rs867229
rs867229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0017921
Disease:
Glycogen storage disease type II
0.010 GeneticVariation BEFREE Single nucleotide polymorphisms (SNP) rs78488639 increased the risk to exudative AMD (P=0.043) and PCV (P=0.016), whereas SNP rs867229 decreased the risk to exudative AMD (P=0.0026), but not PCV. 25277308 2014
dbSNP: rs867229
rs867229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C1504336
Disease:
Polypoidal choroidal vasculopathy
0.010 GeneticVariation BEFREE Exudative AMD, but not PCV, was associated with the heterozygous genotypes of rs2070746 (P=0.019, OR=0.57) and rs867229 (P=0.0082, OR=0.54). 25277308 2014
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0699791
Disease:
Stomach Carcinoma
0.010 GeneticVariation BEFREE Homozygous K alleles of rs1042229 were associated with stomach cancer (Odds ratio [OR]=1.62, confidence interval [CI]=1.05-2.48, p=0.028). 21216225 2011
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0024623
Disease:
Malignant neoplasm of stomach
0.010 GeneticVariation BEFREE Homozygous K alleles of rs1042229 were associated with stomach cancer (Odds ratio [OR]=1.62, confidence interval [CI]=1.05-2.48, p=0.028). 21216225 2011
dbSNP: rs2070745
rs2070745
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0001342
Disease:
Acute periodontitis
0.010 GeneticVariation BEFREE Five polymorphisms (-12915C>T, -10056T>C, -8430A>G, 301G>C, and 546C>A) showed significant association with AgP. 17927965 2007
dbSNP: rs2070745
rs2070745
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0031106
Disease:
Aggressive Periodontitis
0.010 GeneticVariation BEFREE Five polymorphisms (-12915C>T, -10056T>C, -8430A>G, 301G>C, and 546C>A) showed significant association with AgP. 17927965 2007
dbSNP: rs2070746
rs2070746
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0031106
Disease:
Aggressive Periodontitis
0.010 GeneticVariation BEFREE Haplotype association analysis with three SNPs (-12915C>T, 301G>C, and 546C>A) revealed that one haplotype (-12915T-301G-546C) was significantly represented in AgP patients (p=0.000020). 17927965 2007
dbSNP: rs2070746
rs2070746
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0001342
Disease:
Acute periodontitis
0.010 GeneticVariation BEFREE Haplotype association analysis with three SNPs (-12915C>T, 301G>C, and 546C>A) revealed that one haplotype (-12915T-301G-546C) was significantly represented in AgP patients (p=0.000020). 17927965 2007
dbSNP: rs1042229
rs1042229
Entrez Id: 2357
Gene Symbol: FPR1
FPR1
CUI: C0001342
Disease:
Acute periodontitis
0.010 GeneticVariation BEFREE Six SNPs were identified including two located in the FPR1 second extracellular loop that were significantly associated with the AP phenotype in African-American patients (p.R190W, P=0.0033; and p.N192K, P=0.0018). 12595898 2003