DDX58, DExD/H-box helicase 58, 23586

N. diseases: 144; N. variants: 10
Disease: Measles ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs669260
rs669260
Entrez Id: 23586
Gene Symbol: DDX58
DDX58
CUI: C0025007
Disease:
Measles 		0.010 GeneticVariation BEFREE An intronic SNP (rs669260) in the antiviral innate immune receptor gene, DDX58, was significantly associated with increased neutralizing antibody titers for both measles and rubella viral antigens post-MMR vaccination (p values 0.02 and 0.0002, respectively). 25139337 2014
dbSNP: rs3205166
rs3205166
Entrez Id: 23586
Gene Symbol: DDX58
DDX58
CUI: C0025007
Disease:
Measles 		0.010 GeneticVariation BEFREE Genetic variants within the DDX58/RIG-I gene, including a coding polymorphism (rs3205166/Val800Val), were associated as single-SNPs (p≤0.017; although these SNPs did not remain significant after correction for false discovery rate/FDR) and in haplotype-level analysis, with measles-specific antibody variations in Caucasians (haplotype allele p-value=0.021; haplotype global p-value=0.076). 21939710 2011