BACE1, beta-secretase 1, 23621

N. diseases: 120; N. variants: 8
Disease: Alzheimer's Disease ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs638405
rs638405
Entrez Id: 23621;100379571
Gene Symbol: BACE1;BACE1-AS
BACE1;BACE1-AS
CUI: C0002395
Disease:
Alzheimer's Disease 		0.030 GeneticVariation BEFREE By exclusion of three studies that </span>did not conform to Hardy-Weinberg equilibrium (HWE), our data suggested rs638405 in BACE1 was a protective factor of AD. 26846559 2017
dbSNP: rs638405
rs638405
Entrez Id: 23621;100379571
Gene Symbol: BACE1;BACE1-AS
BACE1;BACE1-AS
CUI: C0002395
Disease:
Alzheimer's Disease 		0.030 GeneticVariation BEFREE Our analysis demonstrated that GG genotype and G allele of BACE1 gene rs638405 probably increase the risk of AD. 26828303 2016
dbSNP: rs638405
rs638405
Entrez Id: 23621;100379571
Gene Symbol: BACE1;BACE1-AS
BACE1;BACE1-AS
CUI: C0002395
Disease:
Alzheimer's Disease 		0.030 GeneticVariation BEFREE This study is an attempt to clarify whether the common SNP in exon 5 of BACE1 (rs638405, Val262) is associated with a risk for late-onset AD. 18182766 2008