IL27, interleukin 27, 246778

N. diseases: 286; N. variants: 14
Disease: Ulcerative Colitis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs181206
rs181206
Entrez Id: 246778
Gene Symbol: IL27
IL27
CUI: C0009324
Disease:
Ulcerative Colitis 		0.010 GeneticVariation BEFREE Disease type-stratified subgroup analysis yielded increased risk of related diseases in IL-27 rs181206 T>C carriers in the allele model in immune thrombocytopenia (ITP), asthma, and esophageal cancer (EC) subgroups (ITP: OR=0.69, 95%CI=0.53~0.88, P=0.004; asthma: OR=0.60, 95%CI=0.41~0.89, P=0.010; EC: OR=0.79, 95%CI=0.64~0.97, P=0.026); and IL-27 rs153109 A>G polymorphism was remarkably associated with the increased risk of related diseases in the allele model in ovarian cancer (OC), systemic lupus erythematosus (SLE), tuberculosis (TB), ulcerative colitis (UC), and chronic obstructive pulmonary disease (COPD) subgroups (all P<0.05). 26950245 2016