MTOR, mechanistic target of rapamycin kinase, 2475
N. diseases: 68; N. variants: 36
Source: CURATED ×
| Variant | Gene | Disease | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||||
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T | 0.810 | CausalMutation | CLINVAR | |||||||||
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G | 0.810 | CausalMutation | CLINVAR | |||||||||
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C | 0.810 | CausalMutation | CLINVAR | |||||||||
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C | 0.810 | CausalMutation | CLINVAR | |||||||||
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T | 0.810 | CausalMutation | CLINVAR | |||||||||
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G | 0.800 | CausalMutation | CLINVAR | |||||||||
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C | 0.800 | CausalMutation | CLINVAR | |||||||||
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G | 0.800 | CausalMutation | CLINVAR | |||||||||
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G | 0.800 | CausalMutation | CLINVAR | |||||||||
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T | 0.800 | CausalMutation | CLINVAR | |||||||||
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G | 0.800 | CausalMutation | CLINVAR | |||||||||
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A | 0.800 | CausalMutation | CLINVAR | |||||||||
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T | 0.800 | CausalMutation | CLINVAR | |||||||||
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A | 0.800 | CausalMutation | CLINVAR | |||||||||
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C | 0.800 | CausalMutation | CLINVAR | |||||||||
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T | 0.800 | CausalMutation | CLINVAR | |||||||||
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T | 0.800 | CausalMutation | CLINVAR | |||||||||
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G | 0.700 | GeneticVariation | CLINVAR | A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity. | 24631838 | 2014 | ||||||
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T | 0.700 | GeneticVariation | CLINVAR | Tumor genetic analyses of patients with metastatic renal cell carcinoma and extended benefit from mTOR inhibitor therapy. | 24622468 | 2014 | ||||||
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G | 0.700 | GeneticVariation | CLINVAR | A diverse array of cancer-associated MTOR mutations are hyperactivating and can predict rapamycin sensitivity. | 24631838 | 2014 | ||||||
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T | 0.700 | GeneticVariation | CLINVAR | Activating mTOR mutations in a patient with an extraordinary response on a phase I trial of everolimus and pazopanib. | 24625776 | 2014 | ||||||
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C | 0.700 | GeneticVariation | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 | ||||||
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C | 0.700 | GeneticVariation | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 | ||||||
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C | 0.700 | GeneticVariation | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 | ||||||
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G | 0.700 | GeneticVariation | CLINVAR | Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. | 26619011 | 2016 |