FRZB, frizzled related protein, 2487

N. diseases: 89; N. variants: 8
Disease: Osteoarthritis of hip ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs288326
rs288326
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
CUI: C0029410
Disease:
Osteoarthritis of hip 		0.030 GeneticVariation BEFREE The presence of the rs288326 SNP alters the relationship between proximal femur shape and incident radiographic hip OA. 22544526 2012
dbSNP: rs288326
rs288326
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
CUI: C0029410
Disease:
Osteoarthritis of hip 		0.030 GeneticVariation BEFREE Analyses for FRZB polymorphisms and haplotypes did not reveal any statistically significant signals, except for a borderline association of rs288326 with hip OA (P=0.019). 19479880 2009
dbSNP: rs288326
rs288326
Entrez Id: 2487
Gene Symbol: FRZB
FRZB
CUI: C0029410
Disease:
Osteoarthritis of hip 		0.030 GeneticVariation BEFREE Our data confirm findings of another study, that a rare haplotype with both Arg200Trp and Arg324Gly FRZB variants contributes to the genetic susceptibility to hip OA among Caucasian women, and that these polymorphisms may contribute to increased serum levels of proteins as biomarkers of OA. 16572458 2006