DisGeNET - a database of gene-disease associations

PCSK9, proprotein convertase subtilisin/kexin type 9, 255738

N. diseases: 257; N. variants: 92

Disease: Low density lipoprotein cholesterol measurement ×

Variant: rs11806638 ×

Source: ALL

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _v

DPI _v

pLI

EI _vda

EL _gda

Score _vda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Variant

Gene

Disease

Risk Allele

Score _vda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

dbSNP:

rs11806638

Entrez Id:	255738
Gene Symbol:	PCSK9

PCSK9

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASCAT

Genetic analyses of diverse populations improves discovery for complex traits.

31217584

2019

dbSNP:

rs11806638

Entrez Id:	255738
Gene Symbol:	PCSK9

PCSK9

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASDB

Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.

23236364

2012

dbSNP:

rs11806638

Entrez Id:	255738
Gene Symbol:	PCSK9

PCSK9

CUI:	C0202117
Disease:

Low density lipoprotein cholesterol measurement

0.800

GeneticVariation

GWASDB

Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.

22629316

2012