GCG, glucagon, 2641

N. diseases: 441; N. variants: 10
Disease: Diabetes Mellitus, Non-Insulin-Dependent ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1037733674
rs1037733674
Entrez Id: 2641;101929532
Gene Symbol: GCG;LOC101929532
GCG;LOC101929532
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE Our results show that the Gly40Ser mutation in the glucagon receptor gene is not associated with type 2 diabetes in a Brazilian population. 11961492 2002
dbSNP: rs1037733674
rs1037733674
Entrez Id: 2641;101929532
Gene Symbol: GCG;LOC101929532
GCG;LOC101929532
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE Our results demonstrate a strong genetic heterogeneity among the ethnic group and suggest that the Gly40Ser mutation of the glucagon receptor gene plays little role, if any, in the pathogenesis of type 2 diabetes and essential hypertension in the Taiwanese population. 10090412 1999
dbSNP: rs1037733674
rs1037733674
Entrez Id: 2641;101929532
Gene Symbol: GCG;LOC101929532
GCG;LOC101929532
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE In conclusion, our results indicate that the Gly40Ser variation is not associated with NIDDM in the Sardinian population and that its frequency varies in different parts of Sardinia. 9028723 1997
dbSNP: rs1037733674
rs1037733674
Entrez Id: 2641;101929532
Gene Symbol: GCG;LOC101929532
GCG;LOC101929532
CUI: C0011860
Disease:
Diabetes Mellitus, Non-Insulin-Dependent 		0.040 GeneticVariation BEFREE We have previously reported that a single heterozygous missense mutation in exon 2 of the glucagon receptor gene, which changes a glycine to a serine (Gly40Ser), is associated with NIDDM in a French population. 8635644 1996