GREM1, gremlin 1, DAN family BMP antagonist, 26585

N. diseases: 179; N. variants: 8
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009402
Disease:
Colorectal Carcinoma 		G 0.800 GeneticVariation GWASCAT Novel Common Genetic Susceptibility Loci for Colorectal Cancer. 29917119 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009402
Disease:
Colorectal Carcinoma 		G 0.800 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009402
Disease:
Colorectal Carcinoma 		G 0.800 GeneticVariation GWASDB Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. 24737748 2014
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009402
Disease:
Colorectal Carcinoma 		G 0.800 GeneticVariation GWASCAT Identification of susceptibility loci for colorectal cancer in a genome-wide meta-analysis. 24737748 2014
dbSNP: rs10318
rs10318
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.730 GeneticVariation BEFREE This meta-analysis demonstrated that the rs4779584 and rs10318 polymorphism at 15q13.3 is a risk factor associated with increased CRC/CRA susceptibility, but these associations vary in different ethnic populations. 25475391 2015
dbSNP: rs10318
rs10318
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.730 GeneticVariation BEFREE In two of the five genes originally associated with CRC, we found evidence for association in AAs including rs1862748 in CDH1 (OR(Add) = 0.82, P = 0.02) and in GREM1 the SNPs rs10318 (OR(Rec) = 60.1, P = 0.01), rs11632715 (OR(Rec) = 2.36; P = 0.004) and rs12902616 (OR(Rec) = 1.28, P = 0.005), the latter which is in linkage disequilibrium with the previously identified SNP rs4779584. 24753543 2014
dbSNP: rs10318
rs10318
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.730 GeneticVariation BEFREE At 15q13.3, rs10318 was associated with CRC in both populations. 20659471 2010
dbSNP: rs10318
rs10318
Entrez Id: 26585
Gene Symbol: GREM1
GREM1
CUI: C0009402
Disease:
Colorectal Carcinoma 		0.730 GeneticVariation GWASDB Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer. 19011631 2008
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009404
Disease:
Colorectal Neoplasms 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C2677123
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0007102
Disease:
Malignant tumor of colon 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C1837315
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C2675481
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C3554460
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009402
Disease:
Colorectal Carcinoma 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0346629
Disease:
Malignant neoplasm of large intestine 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs2293581
rs2293581
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C1302401
Disease:
Adenoma of large intestine 		A 0.700 GeneticVariation GWASCAT Discovery of common and rare genetic risk variants for colorectal cancer. 30510241 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C2677123
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3 		G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C3554460
Disease:
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12 		G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009404
Disease:
Colorectal Neoplasms 		G 0.700 GeneticVariation GWASCAT Novel Common Genetic Susceptibility Loci for Colorectal Cancer. 29917119 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C1319315
Disease:
Adenocarcinoma of large intestine 		G 0.700 GeneticVariation GWASCAT Novel Common Genetic Susceptibility Loci for Colorectal Cancer. 29917119 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0009404
Disease:
Colorectal Neoplasms 		G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019
dbSNP: rs73376930
rs73376930
Entrez Id: 26585;100131315
Gene Symbol: GREM1;LOC100131315
GREM1;LOC100131315
CUI: C0007102
Disease:
Malignant tumor of colon 		G 0.700 GeneticVariation GWASCAT Association analyses identify 31 new risk loci for colorectal cancer susceptibility. 31089142 2019