GPC1, glypican 1, 2817

N. diseases: 96; N. variants: 3
Disease: Liver carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE We evaluated the associations of <i>miR-499A</i>>G (rs3746444), <i>miR-149C</i>>T (rs2292832), <i>miR-196a2T</i>>C (rs11614913), and <i>miR-146aG</i>>C (rs2910164) with HCC susceptibility in 100 HCC patients (70 males and 30 females) and 120 healthy controls (70 males and 50 females), using the PCR-restriction fragment length polymorphism method. 30215231 2019
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE And hsa-<i>mir-149</i> rs2292832 was found to be associated with a decreased HBV-related HCC risk in the dominant and recessive models. 29976775 2018
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE To evaluate the association between four common miRNAs (miR-146a rs2910164; miR-149 rs2292832; miR-196a2 rs11614913 and miR-499 rs3746444) and HCC risk, an updated meta-analysis was performed. 28499985 2017
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE Our meta-analysis supports that the MIR-149 gene rs2292832 polymorphism contributed to the risk of HCC from currently available evidence. 27348444 2016
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE In this research, we investigated the role of miR- 149 (rs2292832) and miR-101-1 (rs7536540) with HCC progression in Thai population. 26434859 2015
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE Predictive role of miR-146a rs2910164 (C>G), miR-149 rs2292832 (T>C), miR-196a2 rs11614913 (T>C) and miR-499 rs3746444 (T>C) in the development of hepatocellular carcinoma. 26823863 2015
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE Association study of miR‑149 rs2292832 and miR‑608 rs4919510 and the risk of hepatocellular carcinoma in a large‑scale population. 25190221 2014
dbSNP: rs2292832
rs2292832
Entrez Id: 2817;406941;100130449
Gene Symbol: GPC1;MIR149;LOC100130449
GPC1;MIR149;LOC100130449
CUI: C2239176
Disease:
Liver carcinoma 		0.080 GeneticVariation BEFREE Results of this meta-analysis suggest that the hsa-miR-149 rs2292832 polymorphism is not associated with cancer risk in spite of the potentially protective role of C allele in hepatocellular carcinoma and male gastric cancer. 24040059 2013