ANGPT1, angiopoietin 1, 284

N. diseases: 340; N. variants: 18
Disease: Carcinoma of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4262299
rs4262299
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
CUI: C0684249
Disease:
Carcinoma of lung 		0.010 GeneticVariation BEFREE We checked the interaction effect on the ANGPT1 expression and lung cancer and found that the minor allele "G" of rs1654701 increased ANGPT1 gene expression and decreased lung cancer risk with the increased dosage of "A" of rs4262299, which consistent with the tumor suppressor function of ANGPT1. 31385379 2019