Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE CONCLUSIONS Polymorphisms of GSTP1 rs1695 and ABCC2 rs717620 can be used to predict the outcomes of Uygur patients with advanced NSCLC who have received platinum-based chemotherapy. 28442702 2017
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE In summary, we suggest that GSTP1 Ile105Val and XRCC1 Arg399Gln polymorphisms could influence the response to chemotherapy and sur-vival of advanced NSCLC. 27323109 2016
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE In the Cox proportional hazards model, GG genotype of GSTP1 A313G was significantly correlated with a longer median survival time when compared with AA genotype, and it is associated with a heavy decreased risk of death from NSCLC. 26097600 2015
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE Moreover, individuals carrying both the G/A+G/G genotype of GSTP1 Ile105Val and the G/A+A/A of XRCC1 Arg194Trp were associated with heavy greater CR+PR response to chemotherapy (OR=2.98, 95% CI=1.39-6.42), and also correlated with longer overall survival of advanced NSCLC (HR=0.19, 95% CI=0.05-0.61). 26823821 2015
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE Presence of the GG genotype of GSTP1 rs1695 and the GA and AA genotypes of XRCC1 rs25487 was associated with overall survival of NSCLC, and the hazards ratios (95%CI) were 4.35 (1.40-17.92), 0.53 (0.31-0.91), and 0.39 (0.18-0.83), respectively. 26345972 2015
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE Our study suggested that the GSTP1 A313G and GSTM1 null/present polymorphisms could predict the treatment response of the platinum-based chemotherapy in NSCLC patients, especially in East-Asian patients. 24729086 2014
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE Attention should be paid to MDR1 C3435T, G2677A/T and GSTP1 A313G for personalized chemotherapy treatment for NSCLC patients in Asian population in the future. 22761669 2012
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE The polymorphic status of MRP2 C-24T and GSTP1 Ile105Val might be the predictive markers for the treatment response of advanced NSCLC patients. 19568750 2010
dbSNP: rs1695
rs1695
Entrez Id: 2950
Gene Symbol: GSTP1
GSTP1
CUI: C0007131
Disease:
Non-Small Cell Lung Carcinoma
0.090 GeneticVariation BEFREE In this study, CYP1A1 (Ile462Val), CYP1B1(Asn453Ser), GST M1, GSTP1 exon 5 (Ile105Val) and exon 6(Ala114Val) and GSTT1 polymorphisms were determined in 138 patients with advanced NSCLC to evaluate their role in survival. 20845989 2010