rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Patients with an unexplained microsatellite instable tumour have a low risk of familial cancer.
|
17453009 |
2007 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Molecular analysis of hereditary nonpolyposis colorectal cancer in the United States: high mutation detection rate among clinically selected families and characterization of an American founder genomic deletion of the MSH2 gene.
|
12658575 |
2003 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Constitutional mismatch repair deficiency syndrome: clinical description in a French cohort.
|
26318770 |
2015 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients.
|
18301448 |
2008 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
High prevalence of mismatch repair deficiency in prostate cancers diagnosed in mismatch repair gene mutation carriers from the colon cancer family registry.
|
25117503 |
2014 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
No association between MUTYH and MSH6 germline mutations in 64 HNPCC patients.
|
18301448 |
2008 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Identification and survival of carriers of mutations in DNA mismatch-repair genes in colon cancer.
|
16807412 |
2006 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Germ-line mutation of the hMSH6/GTBP gene in an atypical hereditary nonpolyposis colorectal cancer kindred.
|
9307272 |
1997 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
|
15483016 |
2004 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Lower incidence of colorectal cancer and later age of disease onset in 27 families with pathogenic MSH6 germline mutations compared with families with MLH1 or MSH2 mutations: the German Hereditary Nonpolyposis Colorectal Cancer Consortium.
|
15483016 |
2004 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Risk of urothelial bladder cancer in Lynch syndrome is increased, in particular among MSH2 mutation carriers.
|
20591884 |
2010 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Very low prevalence of germline MSH6 mutations in hereditary non-polyposis colorectal cancer suspected patients with colorectal cancer without microsatellite instability.
|
17117178 |
2006 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Molecular analysis of familial endometrial carcinoma: a manifestation of hereditary nonpolyposis colorectal cancer or a separate syndrome?
|
15837969 |
2005 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers.
|
20587412 |
2010 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Germline mutation in MSH6 associated with multiple malignant neoplasms in a patient With Muir-Torre syndrome.
|
22734033 |
2012 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Germline mutations in a polycytosine repeat of the hMSH6 gene in Korean hereditary nonpolyposis colorectal cancer.
|
9929971 |
1999 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
A massive parallel sequencing workflow for diagnostic genetic testing of mismatch repair genes.
|
24689082 |
2014 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Risks of Lynch syndrome cancers for MSH6 mutation carriers.
|
20028993 |
2010 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Familial endometrial cancer in female carriers of MSH6 germline mutations.
|
10508506 |
1999 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
A |
0.700 |
CausalMutation |
CLINVAR |
Combined iPLEX and TaqMan assays to screen for 45 common mutations in Lynch syndrome and FAP patients.
|
20007843 |
2010 |
rs267608078
|
MSH6;FBXO11
|
Hereditary Nonpolyposis Colorectal Neoplasms
|
AC |
0.700 |
CausalMutation |
CLINVAR |
Molecular and clinical characteristics of MSH6 germline variants detected in colorectal cancer patients.
|
24100870 |
2013 |