CD209, CD209 molecule, 30835

N. diseases: 57; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF). 29054571 2018
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE Because the -336A/G SNP (rs4804803) polymorphism in the promoter of CD209 modulates DC-SIGN expression, we investigated the putative association of this polymorphism with DENV infection and its pathogenesis. 24797508 2014
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE In this study, real-time PCR was used to characterize the distribution of rs1801274 and rs4804803 in subjects with asymptomatic dengue infection (n=145), uncomplicated dengue (n=67), and severe dengue (n=36) in Morelos. 24911936 2014
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE Polymorphisms in the promoter region of CD209 gene (rs735239, rs4804803, rs2287886) were investigated in 112 hospitalized cases of dengue (DEN) and 104 healthy controls to find out whether they are associated with dengue in a Western Indian population. 23624202 2013
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. 22061615 2012
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF. 21245921 2011
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0011311
Disease:
Dengue Fever
0.070 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever. 20470843 2010
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019100
Disease:
Severe Dengue
0.040 GeneticVariation BEFREE The overall meta-analysis revealed significant associations between rs4804803 and severe dengue under the recession (<i>GG</i> versus <i>GA/AA</i>: OR = 0.44, 95%CI, 0.23-0.82) and a codominant model (<i>GG</i> versus <i>AA</i>: OR = 0.43, 95%CI, 0.23-0.81), but sensitivity analysis indicated that the significant pooled ORs were not robust. 31027310 2019
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019100
Disease:
Severe Dengue
0.040 GeneticVariation BEFREE A common CD209-336G/A (rs4804803) polymorphism in DC-SIGN may affect severity of dengue virus infection (DEN) and incidence of dengue fever (DF) or the more severe dengue hemorrhagic fever (DHF). 29054571 2018
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019100
Disease:
Severe Dengue
0.040 GeneticVariation BEFREE The rs1800629 A-allele in the TNF gene was associated with an increased risk of DHF (OR = 3.4, CI = 1.235-9.284 p = 0.0212) whereas SNPs rs4804803, rs2780831, rs1801274, rs231775, rs12979860, and rs8099917 showed no association in this cohort. 29130827 2018
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0041296
Disease:
Tuberculosis
0.040 GeneticVariation BEFREE We screened 4 single nucleotide polymorphisms (SNPs) in the promoter region of CD209, namely -939G>A (rs735240), -871A>G (rs735239), -336A>G (rs4804803) and -139G>A (rs2287886) and tandem repeat polymorphisms in exon 4 of CD209 and CD209L genes looking for association with TB in a Northeastern Brazilian population (295 subjects, 131 TB patients and 164 healthy controls). 24874302 2014
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0041296
Disease:
Tuberculosis
0.040 GeneticVariation BEFREE The primary objective of this study was to investigate this issue in the model of Mycobacterium tuberculosis and human DC-SIGN encoding CD209 promoter SNP (rs4804803) in Russian Siberian population. 22027159 2012
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019100
Disease:
Severe Dengue
0.040 GeneticVariation BEFREE the rs4804803 SNP in the CD209 promoter contributed to susceptibility to dengue infection and complication of DHF. 21245921 2011
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0041296
Disease:
Tuberculosis
0.040 GeneticVariation BEFREE A single nucleotide polymorphism (SNP) in the promoter region of CD209 (-336 A/G; rs4804803) affects transcription and is associated with the severity of tuberculosis and dengue fever. 20470843 2010
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0041296
Disease:
Tuberculosis
0.040 GeneticVariation BEFREE A total of 2,176 individuals enrolled in tuberculosis case-control studies from four sub-Saharan Africa countries were genotyped for the CD209 -336A/G SNP (rs4804803). 18167547 2008
dbSNP: rs2287886
rs2287886
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0014061
Disease:
Tick-Borne Encephalitis
0.020 GeneticVariation BEFREE <b>Results </b>Comparison between TBE patients and CG showed that in SNP rs2287886 CD 209 AG heterozygotes were more frequent in the TBE group, while homozygotes GG were more frequent in the CG group. 28894041 2017
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0042769
Disease:
Virus Diseases
0.020 GeneticVariation BEFREE Among significant associations found between virus infections and genetic variants, we report for the first time an association of rs4804803 (CD209) A and G variants with susceptibility to HBV infection and spontaneous clearance (p<0.001, OR=3.53, 95% CI 2.155; 5.908, and p<0.001, OR=7.75, 95% CI 4.646-13.114, respectively). 24797387 2014
dbSNP: rs2287886
rs2287886
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0014061
Disease:
Tick-Borne Encephalitis
0.020 GeneticVariation BEFREE Thus, our results suggest that the CD209 gene promoter region rs2287886 SNP is associated with predisposition to severe forms of TBE in the Russian population. 22061615 2012
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0042769
Disease:
Virus Diseases
0.020 GeneticVariation BEFREE Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. 22061615 2012
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019196
Disease:
Hepatitis C
0.020 GeneticVariation BEFREE Previously the severity and outcome of dengue fever and hepatitis C (diseases caused by viruses from the family Flaviviridae) were associated with the rs4804803 single nucleotide polymorphism (SNP) located in the promoter region of the human CD209 gene. 22061615 2012
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0019196
Disease:
Hepatitis C
0.020 GeneticVariation BEFREE We conclude that rs4804803, an SNP in the CD209 promoter, contributes to severity of liver disease in chronic HCV infection. 20470843 2010
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0030409
Disease:
Paracoccidioidomycosis
0.010 GeneticVariation BEFREE In the VDR (rs7975232), the CC genotype (P < 0.001, OR = 5.94, 95% CI = 2.07-17.05), and the C allele (P = 0.027, OR = 2.71, 95% CI = 1.07-6.86), as well as the GG genotype in DC-SIGN (rs4804803) (P = 0.032, OR: 3.76, 95%, I = 1.06-13.38) are associated with an increased risk of oral PCM. 30367528 2019
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C0333047
Disease:
Recession
0.010 GeneticVariation BEFREE The overall meta-analysis revealed significant associations between rs4804803 and severe dengue under the recession (<i>GG</i> versus <i>GA/AA</i>: OR = 0.44, 95%CI, 0.23-0.82) and a codominant model (<i>GG</i> versus <i>AA</i>: OR = 0.43, 95%CI, 0.23-0.81), but sensitivity analysis indicated that the significant pooled ORs were not robust. 31027310 2019
dbSNP: rs4804803
rs4804803
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C2931822
Disease:
Nasopharyngeal carcinoma
0.010 GeneticVariation BEFREE At rs4804803, risk of NPC was significantly higher in individuals with the genotype GG than in those with the genotype AA (adjusted OR 9.038, 95%CI 1.708-47.822). 28694559 2017
dbSNP: rs7252229
rs7252229
Entrez Id: 30835
Gene Symbol: CD209
CD209
CUI: C2931822
Disease:
Nasopharyngeal carcinoma
0.010 GeneticVariation BEFREE At rs7252229, risk of NPC was significantly lower in individuals with GC (odds ratio [OR] 0.076, 95% confidence interval [CI] 0.008-0.690), GG (OR 0.056, 95%CI 0.006-0.487), or GC + GG (OR 0.059, 95%CI 0.007-0.515) than in individuals with the CC genotype, after adjusting for age, gender, smoking history, and EBV-VCA-IgA status. 28694559 2017