HIF1A, hypoxia inducible factor 1 subunit alpha, 3091

N. diseases: 1044; N. variants: 15
Disease: Prostate carcinoma ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11549467
rs11549467
Entrez Id: 3091;105370526
Gene Symbol: HIF1A;HIF1A-AS3
HIF1A;HIF1A-AS3
CUI: C0600139
Disease:
Prostate carcinoma 		0.030 GeneticVariation BEFREE The current findings suggest that HIF1A P582S polymorphism correlates with urinary cancers risk in Caucasian population, while A588T polymorphism may increase the risk of urinary cancers in Asian population and prostate cancer. 23723982 2013
dbSNP: rs11549467
rs11549467
Entrez Id: 3091;105370526
Gene Symbol: HIF1A;HIF1A-AS3
HIF1A;HIF1A-AS3
CUI: C0600139
Disease:
Prostate carcinoma 		0.030 GeneticVariation BEFREE However, the combined variant genotypes of rs2057482 and rs11549467 were associated with increased PCa risk (OR=2.10; 95%CI=1.23-3.57 among subjects carrying three or more risk alleles). 23042446 2012
dbSNP: rs11549467
rs11549467
Entrez Id: 3091;105370526
Gene Symbol: HIF1A;HIF1A-AS3
HIF1A;HIF1A-AS3
CUI: C0600139
Disease:
Prostate carcinoma 		0.030 GeneticVariation BEFREE No significant differences were found between the frequencies of A588T mutation in prostate cancer patients and controls. 16998808 2007