rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
0.830
GeneticVariation
BEFREE
Moreover, we replicated the association between rs12191877 (HLA-C) and type I psoriasis and between type I and type II psoriasis .
26613086
2015
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
0.830
GeneticVariation
BEFREE
The results of the univariate analysis showed an association between rs10484879 and psoriasis , although this relationship disappeared after adjustment for HLA-C (rs12191877 ).
26415694
2015
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
0.830
GeneticVariation
GWASCAT
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
20953188
2010
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
0.830
GeneticVariation
GWASDB
Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2.
20953188
2010
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
0.830
GeneticVariation
BEFREE
The most significant finding was for SNP rs12191877 , which is in tight linkage disequilibrium with HLA-Cw*0602, the consensus risk allele for psoriasis .
19680446
2009
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
T
0.830
GeneticVariation
GWASCAT
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
19169254
2009
rs12191877
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Psoriasis
T
0.830
GeneticVariation
GWASDB
Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.
19169254
2009
rs9468925
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Vitiligo
0.820
GeneticVariation
BEFREE
Allele G of rs9468925 on HLA-C-HLA-B may be associated with a higher risk of vitiligo .
21951294
2012
rs9468925
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Vitiligo
0.820
GeneticVariation
BEFREE
More importantly we find that rs9468925 in HLA-C/HLA-B is associated with both psoriasis and vitiligo , providing first important evidence that two major skin diseases share a common genetic locus in the MHC, and a basis for elucidating the molecular mechanism of skin disorders.
22125590
2011
rs9468925
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Vitiligo
0.820
GeneticVariation
GWASDB
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.
20526339
2010
rs9468925
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Vitiligo
0.820
GeneticVariation
GWASCAT
Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC.
20526339
2010
rs10484554
HLA-B;LOC112267902
Psoriasis
0.810
GeneticVariation
BEFREE
We investigated, in 461 psoriatic patients and 454 healthy controls, the associations with psoriasis of four single-nucleotide polymorphisms (SNPs) from the psoriasis susceptibility 1 (PSORS1) interval: rs1062470 (PSORS1C1/CDSN), rs887466 (PSORS1C3), rs2894207 and rs10484554 (LOC105375015).
29589160
2018
rs10484554
HLA-B;LOC112267902
Psoriasis
T
0.810
GeneticVariation
GWASCAT
Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture.
26626624
2015
rs10484554
HLA-B;LOC112267902
Psoriasis
0.810
GeneticVariation
GWASDB
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
20953190
2010
rs10484554
HLA-B;LOC112267902
Psoriasis
0.810
GeneticVariation
GWASCAT
A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.
20953190
2010
rs10484554
HLA-B;LOC112267902
Psoriasis
T
0.810
GeneticVariation
GWASCAT
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
18369459
2008
rs10484554
HLA-B;LOC112267902
Psoriasis
T
0.810
GeneticVariation
GWASDB
A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.
18369459
2008
rs2524079
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
White Blood Cell Count procedure
0.800
GeneticVariation
GWASCAT
Genetic analyses of diverse populations improves discovery for complex traits.
31217584
2019
rs2247056
HLA-B;LINC02571;LOC112267902
Triglycerides measurement
T
0.800
GeneticVariation
GWASCAT
A large electronic-health-record-based genome-wide study of serum lipids.
29507422
2018
rs2524079
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
White Blood Cell Count procedure
G
0.800
GeneticVariation
GWASCAT
Genome-wide association of white blood cell counts in Hispanic/Latino Americans: the Hispanic Community Health Study/Study of Latinos.
28158719
2017
rs2524079
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
White Blood Cell Count procedure
A
0.800
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252
2016
rs3819299
×
Entrez Id:
3106
Gene Symbol:
HLA-B
HLA-B
Platelet Count measurement
G
0.800
GeneticVariation
GWASCAT
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
27863252
2016
rs9264942
HLA-B;LOC112267902
Crohn Disease
0.800
GeneticVariation
GWASCAT
Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations.
26192919
2015
rs2523608
HLA-B;MIR6891
Beta-2-microglobulin measurement
A
0.800
GeneticVariation
GWASCAT
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
23417110
2013
rs2523608
HLA-B;MIR6891
Beta-2-microglobulin measurement
A
0.800
GeneticVariation
GWASDB
Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin.
23417110
2013