Disease: Hepatitis B ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation GWASDB A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. 19349983 2009
dbSNP: rs3135021
rs3135021
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.710 GeneticVariation GWASDB A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. 19349983 2009
dbSNP: rs2301220
rs2301220
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. 19349983 2009
dbSNP: rs9277341
rs9277341
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identifies variants in the HLA-DP locus associated with chronic hepatitis B in Asians. 19349983 2009
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE HLA - DPA1 rs3077 T was strongly associated with decreased risk of chronic HBV infection (odds ratio, .62; P = .001), consistent with the previous report. 21402545 2011
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		G 0.900 GeneticVariation GWASCAT A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		G 0.900 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs3135021
rs3135021
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.710 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs1431399
rs1431399
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs2301220
rs2301220
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs2301226
rs2301226
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs9469341
rs9469341
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population. 21750111 2011
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE Recent genome-wide association studies showed that four single-nucleotide polymorphisms (SNPs) in human leukocyte antigen (HLA)-DP (rs3077 and rs9277535) and HLA-DQ (rs2856718 and rs7453920) were associated with chronic hepatitis B virus (HBV) infection in Japanese populations. 22105689 2012
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE A highly significant association of HLA-DPA1 rs3077 with HBV infection was observed in Caucasians. 22448225 2012
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE The results of meta-analysis pooling all eligible studies also showed that rs3077-A and rs9277535-A alleles were associated with an increased clearance rate to HBV infection (rs3077: OR=0.57, 95% CI=0.44-0.75; rs9277535: OR=0.56, 95% CI=0.47-0.63). 22543033 2012
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		C 0.900 GeneticVariation GWASDB Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. 22737229 2012
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		C 0.900 GeneticVariation GWASCAT Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. 22737229 2012
dbSNP: rs1431403
rs1431403
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean. 22737229 2012
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown to be associated with HBV persistence after acute HBV infection. 23326374 2013
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation BEFREE Our analysis indicated a significant association of rs3077 and rs9277535 in HLA-DP with HBV infection, suggesting that these HLA-DP polymorphisms act beneficially against HBV infection (for rs3077, AG vs. GG: OR = 0.522, 95% CI = 0.485-0.561; AA vs. GG: OR = 0.350, 95% CI = 0.311-0.393; for rs9277535, AG vs. GG: OR = 0.542, 95% CI = 0.506-0.579; AA vs. GG: OR = 0.371, 95% CI = 0.336-0.409). 23601003 2013
dbSNP: rs3077
rs3077
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.900 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs1042169
rs1042169
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.710 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs7770370
rs7770370
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.710 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs9277378
rs9277378
Entrez Id: 3113;3115
Gene Symbol: HLA-DPA1;HLA-DPB1
HLA-DPA1;HLA-DPB1
CUI: C0019163
Disease:
Hepatitis B 		0.710 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013
dbSNP: rs10214910
rs10214910
Entrez Id: 3113
Gene Symbol: HLA-DPA1
HLA-DPA1
CUI: C0019163
Disease:
Hepatitis B 		0.700 GeneticVariation GWASDB A genome-wide association study identified new variants associated with the risk of chronic hepatitis B. 23760081 2013