Disease: Idiopathic Membranous Glomerulonephritis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2187668
rs2187668
Entrez Id: 3117;3118;107986589
Gene Symbol: HLA-DQA1;HLA-DQA2;LOC107986589
HLA-DQA1;HLA-DQA2;LOC107986589
CUI: C0086445
Disease:
Idiopathic Membranous Glomerulonephritis 		0.040 GeneticVariation BEFREE Our pooled analysis showed a significant association between rs2187668-(A) allele and iMN susceptibility, and the intervention of this mutation might bring new therapeutic strategy for iMN. 30383665 2018
dbSNP: rs2187668
rs2187668
Entrez Id: 3117;3118;107986589
Gene Symbol: HLA-DQA1;HLA-DQA2;LOC107986589
HLA-DQA1;HLA-DQA2;LOC107986589
CUI: C0086445
Disease:
Idiopathic Membranous Glomerulonephritis 		0.040 GeneticVariation BEFREE Allelic frequency distributions for SNP rs2187668 within HLA-DQA1 were significantly different between the iMN and control groups. 28849274 2018
dbSNP: rs2187668
rs2187668
Entrez Id: 3117;3118;107986589
Gene Symbol: HLA-DQA1;HLA-DQA2;LOC107986589
HLA-DQA1;HLA-DQA2;LOC107986589
CUI: C0086445
Disease:
Idiopathic Membranous Glomerulonephritis 		0.040 GeneticVariation BEFREE Even under dominant model, the two SNPs were still significantly associated with IMN (P = 3.50×10-3 for rs28383345 and P = 6.55×10-5 for rs2187668). 28685717 2017
dbSNP: rs2187668
rs2187668
Entrez Id: 3117;3118;107986589
Gene Symbol: HLA-DQA1;HLA-DQA2;LOC107986589
HLA-DQA1;HLA-DQA2;LOC107986589
CUI: C0086445
Disease:
Idiopathic Membranous Glomerulonephritis 		0.040 GeneticVariation BEFREE We believe this will be a valuable technique for determining the genotype of rs2187668 and rs4664308 and for assessing individual susceptibility to IMN. 23194743 2013