APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681
Disease: Colorectal Neoplasms ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Genetic analysis in APC, KRAS, and TP53 in patients with stomach and colon cancer. 24861525 2015
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Prospective enterprise-level molecular genotyping of a cohort of cancer patients. 25157968 2014
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Comprehensive molecular characterization of human colon and rectal cancer. 22810696 2012
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR A single-nucleotide substitution mutator phenotype revealed by exome sequencing of human colon adenomas. 23204322 2012
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR "APC mutations in sporadic colorectal tumors: A mutational ""hotspot"" and interdependence of the ""two hits""." 10737795 2000
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Characteristics of somatic mutation of the adenomatous polyposis coli gene in colorectal tumors. 8187091 1994
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene. 1338904 1992
dbSNP: rs121913327
rs121913327
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0009404
Disease:
Colorectal Neoplasms 		T 0.700 GeneticVariation CLINVAR APC mutations occur early during colorectal tumorigenesis. 1528264 1992