APC, APC regulator of WNT signaling pathway, 324

N. diseases: 703; N. variants: 681
Disease: Carcinogenesis ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs137854573
rs137854573
Entrez Id: 324
Gene Symbol: APC
APC
CUI: C0596263
Disease:
Carcinogenesis 		0.010 GeneticVariation BEFREE The mutation of APC (rs137854573, c.C1606T, p.R536X) could result in HB carcinogenesis by activating Wnt signaling. 30619485 2018