rs1366901063
|
HSPA8;SNORD14C;SNORD14D;LOC101929289
|
Parkinson Disease
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings may provide novel insights into the molecular links between alpha-synuclein and UCH-L1 and suggest that aberrant interaction of mutant UCH-L1 with CMA machinery, at least partly, underlies the pathogenesis of PD associated with I93M UCH-L1.
|
18550537 |
2008 |
rs1366901063
|
HSPA8;SNORD14C;SNORD14D;LOC101929289
|
Sporadic Parkinson disease
|
|
0.010 |
GeneticVariation |
BEFREE |
We propose that aberrant interactions of UCH-L1 variants with CMA machinery, at least partly, underlie the pathogenesis of I93M UCH-L1-associated PD, and possibly of sporadic PD.
|
18635949 |
2008 |
rs2236659
|
HSPA8;LOC101929289
|
Coronary heart disease
|
|
0.010 |
GeneticVariation |
BEFREE |
These findings suggest that genetic variants in HSPA8 gene (especially promoter SNP rs2236659) contribute to the CHD susceptibility by affecting its expression level.
|
20300519 |
2010 |
rs1136141
|
HSPA8;LOC101929289
|
Psychotic episodes
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed that FEP patients presented a polymorphism differentiation related to the HSPA8 gene (rs1136141), and a higher frequency of T carriers compared to healthy controls was observed.
|
24548631 |
2014 |
rs4802
|
HSPA8;SNORD14E
|
HIV Infections
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.
|
26148204 |
2015 |
rs4802
|
HSPA8;SNORD14E
|
Creatinine clearance measurement
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.
|
26148204 |
2015 |
rs4936770
|
HSPA8;SNORD14E
|
Creatinine clearance measurement
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.
|
26148204 |
2015 |
rs4936770
|
HSPA8;SNORD14E
|
HIV Infections
|
|
0.700 |
GeneticVariation |
GWASCAT |
Genomewide association study of tenofovir pharmacokinetics and creatinine clearance in AIDS Clinical Trials Group protocol A5202.
|
26148204 |
2015 |
rs2236659
|
HSPA8;LOC101929289
|
Finding of Mean Corpuscular Hemoglobin
|
|
0.700 |
GeneticVariation |
GWASCAT |
Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
|
30595370 |
2019 |