BIRC5, baculoviral IAP repeat containing 5, 332

N. diseases: 199; N. variants: 11
Disease: Primary malignant neoplasm ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE On the other hand, rs17878467 variant plays an important role in prevent the tumorigenicity of urinary cancer in allele contrast model (OR = 0.672, P = 0.009), heterozygote contrast model (OR = 0.585, P = 0.006) and dominant contrast model (OR = 0.595, P = 0.004). 31809840 2020
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE What's more, rs17878467 polymorphism may play a protect role in the tumorigenesis of urinary cancer, shown in heterozygote comparison model (MW vs. WW: OR = 0.882, 95% CI = 0.78-0.999, P = 0.048). 30463805 2019
dbSNP: rs17878467
rs17878467
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
CUI: C1306459
Disease:
Primary malignant neoplasm 		0.030 GeneticVariation BEFREE The findings did not support an association between rs1042489, rs2071214, rs8073069, and rs17878467 polymorphisms and risk of cancer. 30747314 2019