HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Major depression, single episode ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0024517
Disease:
Major depression, single episode 		0.020 GeneticVariation BEFREE We studied the association of rs6295 with the amount of stress in early life and preceding hospitalization for a major depressive episode in course of bipolar disorder. 21397953 2011
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0024517
Disease:
Major depression, single episode 		0.020 GeneticVariation BEFREE In order to further delineate the impact of 5-HT1A gene variation on pharmacoresponse in depression over 6 weeks of antidepressant treatment, the influence of the 5-HT1A-1019C/G (rs6295) polymorphism was investigated in 340 Caucasian patients with a Major Depressive Episode (DSM-IV) with particular attention to the subtype of depression (major depression and melancholic depression). 18387740 2008