HTR1A, 5-hydroxytryptamine receptor 1A, 3350

N. diseases: 229; N. variants: 9
Disease: Schizophrenia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0036341
Disease:
Schizophrenia 		0.050 GeneticVariation BEFREE Meta-analysis of five studies, including the three with lurasidone, showed that rs6295 was associated with improvement in positive (p = 0.023) and negative (p ≤ 0.0001) symptoms in EUR patients with schizophrenia. 31636356 2020
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0036341
Disease:
Schizophrenia 		0.050 GeneticVariation BEFREE Our finding showed that the rs6295 SNP, as a suspected variant that indicates susceptibility to schizophrenia, exhibited a higher transcriptional activity. 27939355 2017
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0036341
Disease:
Schizophrenia 		0.050 GeneticVariation BEFREE The combined effects of the 5- HTTLPR and HTR1A rs6295 polymorphisms modulate decision making in schizophrenia patients. 23036158 2013
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0036341
Disease:
Schizophrenia 		0.050 GeneticVariation BEFREE Two association studies for schizophrenia and three association studies for BP, including this study, met our criteria for the meta-analysis of rs6295. 20594600 2011
dbSNP: rs6295
rs6295
Entrez Id: 3350
Gene Symbol: HTR1A
HTR1A
CUI: C0036341
Disease:
Schizophrenia 		0.050 GeneticVariation BEFREE Huang and colleagues reported that rs6295 in HTR1A was associated with schizophrenia. 19747927 2010