HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C4285807
Disease:
Behavioral and psychological symptoms of dementia
0.030 GeneticVariation BEFREE 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease. 15211529 2004
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0002395
Disease:
Alzheimer's Disease
0.100 GeneticVariation BEFREE 5-HT2A T102C receptor polymorphism and neuropsychiatric symptoms in Alzheimer's disease. 15211529 2004
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011581
Disease:
Depressive disorder
0.050 GeneticVariation BEFREE 5-HT2A receptor gene polymorphism rs6313 was associated with 5-HT2A receptor binding potential, with the ability of individuals to use environmental support in order to prevent depression, and with sleep improvement after antidepressant treatment with mirtazapine. 18801406 2008
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0344315
Disease:
Depressed mood
0.050 GeneticVariation BEFREE 5-HT2A receptor gene polymorphism rs6313 was associated with 5-HT2A receptor binding potential, with the ability of individuals to use environmental support in order to prevent depression, and with sleep improvement after antidepressant treatment with mirtazapine. 18801406 2008
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0011570
Disease:
Mental Depression
0.050 GeneticVariation BEFREE 5-HT2A receptor gene polymorphism rs6313 was associated with 5-HT2A receptor binding potential, with the ability of individuals to use environmental support in order to prevent depression, and with sleep improvement after antidepressant treatment with mirtazapine. 18801406 2008
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease:
Borderline Personality Disorder
0.010 GeneticVariation BEFREE 5-HTTVNTR and MAOA-LPR may have independent predictive effects on co-morbid BPD in female heroin-dependent patients; the gene-gene interactions between MAOA-LPR and 5-HTTVNTR, and among MAOA-LPR, 5-HTTVNTR and rs6311 might also be involved in the etiology of this co-morbidity. 24355137 2014
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0549622
Disease:
Sexual Dysfunction
0.010 GeneticVariation BEFREE 5HT2A (rs6311) single nucleotide polymorphism (SNP) was found to have significant association with SD. 23857836 2013
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia
0.050 GeneticVariation BEFREE T102C polymorphism of the 5-HT2A receptor gene is not associated with the etiology of FS. 11732859 2001
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0155626
Disease:
Acute myocardial infarction
0.020 GeneticVariation BEFREE T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. 17713649 2007
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0085580
Disease:
Essential Hypertension
0.020 GeneticVariation BEFREE T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. 17713649 2007
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0001973
Disease:
Alcoholic Intoxication, Chronic
0.040 GeneticVariation BEFREE T102C polymorphism of the serotonin receptor 2A gene (5-HT2A) has been shown to be associated with certain diseases such as non-fatal acute myocardial infarction, essential hypertension, and alcoholism. 17713649 2007
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C1656427
Disease:
Early onset schizophrenia
0.010 GeneticVariation BEFREE T102C polymorphism of serotonin 2A type receptor gene confers susceptibility to (early onset) schizophrenia in Han Chinese: an association study and meta-analysis. 23857788 2013
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C3714760
Disease:
Drug-induced tardive dyskinesia
0.020 GeneticVariation BEFREE A T102C-His452Tyr haplotype was significantly associated with TD (p=0.0008). 15857569 2005
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0686347
Disease:
Tardive Dyskinesia
0.020 GeneticVariation BEFREE A T102C-His452Tyr haplotype was significantly associated with TD (p=0.0008). 15857569 2005
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0005586
Disease:
Bipolar Disorder
0.050 GeneticVariation BEFREE A number of studies have assessed a relationship between the T102C polymorphism in the HTR2A gene with an increased risk of major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia (SCZ). 24962835 2014
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006012
Disease:
Borderline Personality Disorder
0.010 GeneticVariation BEFREE A number of studies have assessed a relationship between the T102C polymorphism in the HTR2A gene with an increased risk of major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia (SCZ). 24962835 2014
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0006287
Disease:
Bronchopulmonary Dysplasia
0.010 GeneticVariation BEFREE A number of studies have assessed a relationship between the T102C polymorphism in the HTR2A gene with an increased risk of major depressive disorder (MDD), bipolar disorder (BPD), and schizophrenia (SCZ). 24962835 2014
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0028768
Disease:
Obsessive-Compulsive Disorder
0.060 GeneticVariation BEFREE A previous study showed that a single nucleotide polymorphism (SNP), -1438G/A (rs6311), found in the transcriptional control region of the gene that encodes the serotonin-receptor 2A (HTR2A) was associated with obsessive-compulsive disorder (OCD) in a sample of children and adolescents. 21874579 2012
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0021125
Disease:
Impulsive Behavior
0.060 GeneticVariation BEFREE A priori SNP analyses revealed a significant association between the combined impulsivity phenotype and two SNPs within the 5-HT2a receptor gene (HTR2A; rs6313 and rs6311). 29120849 2018
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0021125
Disease:
Impulsive Behavior
0.020 GeneticVariation BEFREE A priori SNP analyses revealed a significant association between the combined impulsivity phenotype and two SNPs within the 5-HT2a receptor gene (HTR2A; rs6313 and rs6311). 29120849 2018
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0030662
Disease:
Gambling, Pathological
0.010 GeneticVariation BEFREE A significant association of the C/C genotype of the serotonin receptor 2A T102C (rs 6313) polymorphism and the PG phenotype was observed [OR = 1.7 (1.1-3.4)]. 22740152 2013
dbSNP: rs75634836
rs75634836
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0030319
Disease:
Panic Disorder
0.020 GeneticVariation BEFREE A significant relationship was found between the COMT Val158Met polymorphism and PD. 22036916 2012
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0036341
Disease:
Schizophrenia
0.100 GeneticVariation BEFREE A statistically significant association between a silent mutation (102T/C) in the serotonin-2A (5-HT2A) receptor gene and schizophrenia has recently been reported in a sample of Japanese patients and healthy controls. 8655141 1996
dbSNP: rs6314
rs6314
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C3714760
Disease:
Drug-induced tardive dyskinesia
0.020 GeneticVariation BEFREE A T102C-His452Tyr haplotype was significantly associated with TD (p=0.0008). 15857569 2005
dbSNP: rs6314
rs6314
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0686347
Disease:
Tardive Dyskinesia
0.020 GeneticVariation BEFREE A T102C-His452Tyr haplotype was significantly associated with TD (p=0.0008). 15857569 2005