HTR2A, 5-hydroxytryptamine receptor 2A, 3356

N. diseases: 289; N. variants: 34
Disease: Fibromyalgia ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia 		0.050 GeneticVariation BEFREE However, meta-analysis of the C allele, CC + CT genotype, and CC versus TT genotype of the 5-HT2A receptor 102T/C p</span>olymorphism showed significant association with fibromyalgia. 21120487 2012
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia 		0.050 GeneticVariation BEFREE Influence of the interaction between environmental quality and T102C SNP in the HTR2A gene on fibromyalgia susceptibility. 22124593 2011
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia 		0.050 GeneticVariation BEFREE The objective of this study was to determine the potential effects of single nucleotide polymorphisms (SNPs) in catechol-O-methyltransferase (COMT) (rs4680) and 5-hydroxytryptamine (serotonin) 2A (5-HT2A) receptor (rs6313 and rs6311) genes on susceptibility to FMS. 18196244 2008
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia 		0.050 GeneticVariation BEFREE T102C polymorphism of the 5-HT2A receptor gene is not associated with the etiology of FS. 11732859 2001
dbSNP: rs6313
rs6313
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0016053
Disease:
Fibromyalgia 		0.050 GeneticVariation BEFREE However, the T102C polymorphism is not directly involved in the aetiology of FM but might be in linkage dysequilibrium with the true functional variant, which has to be unravelled. 10527809 1999