Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0041696
Disease:
Unipolar Depression
0.050 GeneticVariation BEFREE We investigated whether single nucleotide polymorphisms (SNPs) associated with neuroplasticity and activity of monoamine neurotransmitters, such as the brain-derived neurotrophic factor (BDNF, rs6265), the serotonin transporter (SLC6A4, rs25531), the tryptophan hydroxylase 1 (TPH1, rs1800532), the 5-hydroxytryptamine receptor 2A (HTR2A, rs6311, rs6313, rs7997012), and the catechol-O-methyltransferase (COMT, rs4680) genes, are associated with efficacy of transcranial direct current stimulation (tDCS) in major depression. 31721892 2019
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0041696
Disease:
Unipolar Depression
0.050 GeneticVariation BEFREE The study aimed to determine the prevalence of female sexual dysfunction (FSD), its clinical correlates, and association with 5HT2A (rs6311) single nucleotide polymorphisms (SNPs) in patients with major depressive disorder (MDD) who were on SSRI therapy. 24533444 2014
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0041696
Disease:
Unipolar Depression
0.050 GeneticVariation BEFREE Meta-analysis of association between the -1438A/G (rs6311) polymorphism of the serotonin 2A receptor gene and major depressive disorder. 23317793 2013
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0041696
Disease:
Unipolar Depression
0.050 GeneticVariation BEFREE The most replicated findings are the associations between rs6295 (HTR1A gene) G allele or G/G genotype and rs6311 (HTR2A gene) A allele or A/A genotype and MD or depressive symptoms. 23547754 2013
dbSNP: rs6311
rs6311
Entrez Id: 3356
Gene Symbol: HTR2A
HTR2A
CUI: C0041696
Disease:
Unipolar Depression
0.050 GeneticVariation BEFREE No relationship found between -1438A/G polymorphism of the serotonin 2A receptor gene (rs6311) and major depression susceptibility in a northeastern Thai population. 20589614 2010