HTR2C, 5-hydroxytryptamine receptor 2C, 3358

N. diseases: 140; N. variants: 11
Disease: Abnormal behavior ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs6318
rs6318
Entrez Id: 3358;105373313
Gene Symbol: HTR2C;LOC105373313
HTR2C;LOC105373313
CUI: C0233514
Disease:
Abnormal behavior 		0.030 GeneticVariation BEFREE The best minimal model found emotional abuse, recent SLEs, rs9983925 and rs6318 as independent SA risk factors, and general traumas as a factor moderating the effect of psychiatric disorders and emotional abuse. 25732952 2015
dbSNP: rs6318
rs6318
Entrez Id: 3358;105373313
Gene Symbol: HTR2C;LOC105373313
HTR2C;LOC105373313
CUI: C0233514
Disease:
Abnormal behavior 		0.030 GeneticVariation BEFREE Despite the association of Cys23Ser to CSF MHPG, HTR2C genotype was not associated with alcoholism, nor with other psychiatric disorders present in this sample. 10494451 1999
dbSNP: rs6318
rs6318
Entrez Id: 3358;105373313
Gene Symbol: HTR2C;LOC105373313
HTR2C;LOC105373313
CUI: C0233514
Disease:
Abnormal behavior 		0.030 GeneticVariation BEFREE There is a common polymorphism of the human 5-HT2C receptor at codon 23 (cys23ser) which has been reported to be a risk factor for certain psychiatric disorders and a predictor of their pharmacotherapeutic response. 10412190 1999