UBAC2, UBA domain containing 2, 337867

N. diseases: 97; N. variants: 16
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs9557195
rs9557195
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.800 GeneticVariation GWASCAT Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. 28067908 2017
dbSNP: rs9557195
rs9557195
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		T 0.800 GeneticVariation GWASDB Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs9557195
rs9557195
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		T 0.800 GeneticVariation GWASCAT Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. 23128233 2012
dbSNP: rs1887704
rs1887704
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0264408
Disease:
Childhood asthma 		0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs1887704
rs1887704
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0264408
Disease:
Childhood asthma 		G 0.700 GeneticVariation GWASCAT Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies. 31036433 2019
dbSNP: rs1887704
rs1887704
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004096
Disease:
Asthma 		G 0.700 GeneticVariation GWASCAT Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. 30929738 2019
dbSNP: rs1927729
rs1927729
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0751676
Disease:
Basal Cell Cancer 		A 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs1927729
rs1927729
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0206710
Disease:
Basal Cell Neoplasm 		A 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs1927729
rs1927729
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0007117
Disease:
Basal cell carcinoma 		A 0.700 GeneticVariation GWASCAT Combined analysis of keratinocyte cancers identifies novel genome-wide loci. 31174203 2019
dbSNP: rs59186511
rs59186511
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004096
Disease:
Asthma 		C 0.700 GeneticVariation GWASCAT Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis. 31619474 2019
dbSNP: rs912131
rs912131
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0200638
Disease:
Eosinophil count procedure 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs912131
rs912131
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0035242
Disease:
Respiratory Tract Diseases 		0.700 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370 2019
dbSNP: rs9513593
rs9513593
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0033860
Disease:
Psoriasis 		G 0.700 GeneticVariation GWASCAT Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants. 28537254 2017
dbSNP: rs2182885
rs2182885
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0200638
Disease:
Eosinophil count procedure 		A 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2182885
rs2182885
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0200641
Disease:
Blood basophil count (lab test) 		A 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs7332672
rs7332672
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0200638
Disease:
Eosinophil count procedure 		T 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs9557207
rs9557207
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C1704436
Disease:
Peripheral Arterial Diseases 		0.700 GeneticVariation GWASCAT Genetic Variants in the Bone Morphogenic Protein Gene Family Modify the Association between Residential Exposure to Traffic and Peripheral Arterial Disease. 27082954 2016
dbSNP: rs3742130
rs3742130
Entrez Id: 2841;337867
Gene Symbol: GPR18;UBAC2
GPR18;UBAC2
CUI: C0010346
Disease:
Crohn Disease 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs3742130
rs3742130
Entrez Id: 2841;337867
Gene Symbol: GPR18;UBAC2
GPR18;UBAC2
CUI: C0009324
Disease:
Ulcerative Colitis 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs3742130
rs3742130
Entrez Id: 2841;337867
Gene Symbol: GPR18;UBAC2
GPR18;UBAC2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		G 0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs9557207
rs9557207
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0021390
Disease:
Inflammatory Bowel Diseases 		0.700 GeneticVariation GWASCAT Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations. 26192919 2015
dbSNP: rs1466524306
rs1466524306
Entrez Id: 1880;337867
Gene Symbol: GPR183;UBAC2
GPR183;UBAC2
CUI: C0023467
Disease:
Leukemia, Myelocytic, Acute 		0.700 GeneticVariation UNIPROT
dbSNP: rs727263
rs727263
Entrez Id: 337867;100131561
Gene Symbol: UBAC2;FKSG29
UBAC2;FKSG29
CUI: C0026769
Disease:
Multiple Sclerosis 		0.010 GeneticVariation BEFREE Three independent SNPs located within SE showed suggestive evidence of association with MS: rs12928822 (odds ratio (OR)=0.81, 95% confidence interval (CI)=0.73-0.89, P=2.48E-05), rs727263 (OR=0.75, 95% CI=0.66-0.85, P=3.26E-06) and rs4674923 (OR=0.85, 95% CI=0.79-0.92, P=1.63E-05). 24522295 2014
dbSNP: rs9513584
rs9513584
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004943
Disease:
Behcet Syndrome 		0.010 GeneticVariation BEFREE The first-stage study results showed that UBAC2 (rs9513584, Pc = 0.018, OR = 1.4), but not LOC100129342, KIAA1529, CPVL, UBASH3B was associated with the susceptibility to BD in Chinese Han. 22455605 2012
dbSNP: rs9517668
rs9517668
Entrez Id: 337867
Gene Symbol: UBAC2
UBAC2
CUI: C0004943
Disease:
Behcet Syndrome 		0.010 GeneticVariation BEFREE The fine-mapping association study of UBAC2 identified six risk SNPs for BD in the Chinese cohort; three of them were verified in validation study (rs3825427, first-stage Pc = 2.2 × 10-3, second-stage Pc = 9.3 × 10-3, combined Pc = 6.9 × 10-6; rs9517668, first-stage Pc = 1.7 × 10-3, second-stage Pc = 0.03, combined Pc = 3.3 × 10-4; rs9517701, first-stage Pc = 5.1 × 10-3, second-stage Pc = 9.0 × 10-3, combined Pc = 2.9 × 10-5; respectively). 22455605 2012