|
rs5498
|
ICAM1;ICAM4
|
Blood Protein Measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs75407602
|
ICAM1;ICAM4
|
Blood Protein Measurement
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genomic atlas of the human plasma proteome.
|
29875488 |
2018 |
|
rs5498
|
ICAM1;ICAM4
|
Lymphocyte Count measurement
|
G |
0.700 |
GeneticVariation |
GWASCAT |
The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
|
27863252 |
2016 |
|
rs5030383
|
ICAM1;ICAM4
|
Triglycerides measurement
|
|
0.700 |
GeneticVariation |
GWASDB |
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
23063622 |
2012 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
As their main finding, they concluded that 'K469E polymorphism is associated with CHD risk and the K allele is a more significant risk factor for developing CHD amongst Chinese and Caucasians populations'.
|
31072912 |
2019 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
The ICAM1 rs5498 might be a susceptible factor for T2D, but not T1D.
|
30798334 |
2019 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The pooled result showed that the <i>ICAM-1</i> gene E469K</span> polymorphism was significantly associated with an increased risk of CHD (OR = 1.20, 95% CI = 1.11-1.29, for the allele K versus allele E; OR = 1.66, 95% CI = 1.43-1.92, for the K allele carriers versus EE).
|
30674642 |
2019 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
Association between diabetic retinopathy in type 2 diabetes and the ICAM-1 rs5498 polymorphism: a meta-analysis of case-control studies.
|
30419874 |
2018 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease.
|
30290609 |
2018 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
The EE genotype of the rs5498 of the ICAM-1 gene was associated with a more rapid progression of carotid atherosclerosis in patients with T2DM in comparison with other genotypes.
|
27090396 |
2016 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
Our results revealed that SNP rs5498 in ICAM-1 gene and IVS5-13insC variant in HMGA1 gene were not associated with the susceptibility of DR in the Chinese T2DM cohort.
|
26717491 |
2016 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
Association between the ICAM-1 K469E polymorphism and diabetic retinopathy in Type 2 diabetes mellitus: a meta-analysis.
|
24612665 |
2014 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
Intercellular adhesion molecule-1 K469E polymorphism and risk of coronary artery disease: a meta-analysis.
|
25503951 |
2014 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The ICAM-1 K469E polymorphism is associated with the risk of coronary artery disease: a meta-analysis.
|
25025994 |
2014 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
In conclusion, it was demonstrated in the present study that the rs5498 polymorphism of the ICAM‑1 gene was associated with CHD in males.
|
24993975 |
2014 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
Intercellular adhesion molecule-1 E469K gene polymorphism and coronary artery disease in the Chinese population: a meta-analysis involving 3065 subjects.
|
21987404 |
2012 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
The pooled result showed that the ICAM1 gene-E469K</span> polymorphism was significantly associated with an increased risk of CHD (OR = 1.496, 95% CI = 1.363-1.642, for the allele K vs. allele E; OR = 1.919, 95% CI = 11.635-2.253, for the K allele carriers vs. EE).
|
22203486 |
2012 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary heart disease
|
|
0.090 |
GeneticVariation |
BEFREE |
Interactions between rs5498 polymorphism in the ICAM1 gene and traditional risk factors influence susceptibility to coronary artery disease.
|
19048183 |
2009 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
We may conclude that the EE genotype of the K469E polymorphism of the ICAM-1 might be a risk factor for PDR in the Slovenian population (Caucasians) with type 2 diabetes.
|
18942221 |
2008 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
The ICAM-1 gene K469E polymorphism is associated with diabetic retinopathy in Chinese patients with Type 2 diabetes.
|
16759306 |
2006 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
In conclusion, the K469</span>E polymorphism of the ICAM-1 gene was not associated with MI in patients with type 2 diabetes, and therefore may not be used as a genetic marker for MI in patients with type 2 diabetes.
|
17089918 |
2006 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetes Mellitus, Non-Insulin-Dependent
|
|
0.090 |
GeneticVariation |
BEFREE |
The K469E polymorphism of the intercellular adhesion molecule-1 gene is associated with plasma fibrinogen level in type 2 diabetes.
|
15736117 |
2005 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary Artery Disease
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, this meta-analysis indicates that ICAM-1 gene rs5498 polymorphism decreases the risk of CAD.
|
30290609 |
2018 |
|
rs5498
|
ICAM1;ICAM4
|
Coronary Arteriosclerosis
|
|
0.060 |
GeneticVariation |
BEFREE |
ICAM-1 gene rs5498 polymorphism decreases the risk of coronary artery disease.
|
30290609 |
2018 |
|
rs5498
|
ICAM1;ICAM4
|
Diabetic Retinopathy
|
|
0.060 |
GeneticVariation |
BEFREE |
Our meta-analyses provide no evidence of the association of rs5498 with DR in type 2 diabetic patients.
|
30419874 |
2018 |