rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
T
0.740
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011
2016
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
22397365
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.
22397365
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
T
0.740
CausalMutation
CLINVAR
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia.
22417203
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
T
0.740
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
The role of mutations in epigenetic regulators in myeloid malignancies.
22898539
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
0.740
GeneticVariation
BEFREE
The frequency of IDH1/2 mutations was 56%, and the IDH1 R132C mutation, which is not common in diffuse gliomas or AML , accounted for 40% of these mutations.
22323113
2012
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010
2011
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
T
0.740
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010
2011
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
Impact of genetic features on treatment decisions in AML.
22160010
2011
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
C
0.740
CausalMutation
CLINVAR
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C , all IDH1 and IDH2 missense mutations were observed in patients with AML .
20946881
2010
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
0.740
GeneticVariation
BEFREE
IDH1 mutations included R132C (n=4; two post-PMF AML , one post-PV AML and one PMF) and R132S (n=1; post-PMF AML ).
20410924
2010
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C , all IDH1 and IDH2 missense mutations were observed in patients with AML .
20946881
2010
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
0.740
GeneticVariation
BEFREE
Except for one non-Hodgkin lymphoma (NHL) patient harboring IDH1 mutation p.R132C , all IDH1 and IDH2 missense mutations were observed in patients with AML .
20946881
2010
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
0.740
GeneticVariation
BEFREE
The IDH1 R132C mutation commonly found in AML reduces the affinity for isocitrate, and increases the affinity for NADPH and alpha-KG.
20142433
2010
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
T
0.740
CausalMutation
CLINVAR
Recurring mutations found by sequencing an acute myeloid leukemia genome.
19657110
2009
rs121913499
×
Entrez Id:
3417
Gene Symbol:
IDH1
IDH1
Leukemia, Myelocytic, Acute
A
0.740
CausalMutation
CLINVAR
Recurring mutations found by sequencing an acute myeloid leukemia genome.
19657110
2009