IDH2, isocitrate dehydrogenase (NADP(+)) 2, 3418

N. diseases: 380; N. variants: 15
Disease: Angioimmunoblastic Lymphadenopathy ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913503
rs121913503
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0020981
Disease:
Angioimmunoblastic Lymphadenopathy 		0.020 GeneticVariation BEFREE Expression of TFH Markers and Detection of RHOA p.G17V and IDH2 p.R172K/S Mutations in Cutaneous Localizations of Angioimmunoblastic T-Cell Lymphomas. 28945625 2017
dbSNP: rs121913503
rs121913503
Entrez Id: 3418
Gene Symbol: IDH2
IDH2
CUI: C0020981
Disease:
Angioimmunoblastic Lymphadenopathy 		0.020 GeneticVariation BEFREE The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development. 27956631 2016