APOE, apolipoprotein E, 348

N. diseases: 1049; N. variants: 62
Disease: Dyslipidemias ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs429358
rs429358
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0242339
Disease:
Dyslipidemias 		0.020 GeneticVariation BEFREE After taking into account confounding factors and correcting for multiple comparisons only APOE rs429358 and rs7412 variants remained significantly associated with risk of dyslipidemia. 26043189 2015
dbSNP: rs429358
rs429358
Entrez Id: 348
Gene Symbol: APOE
APOE
CUI: C0242339
Disease:
Dyslipidemias 		0.020 GeneticVariation BEFREE ApoE4 which differs from apoE3 by the single amino acid substitution Cys112Arg is also associated with dyslipidemia although binding of this isoform to the LDLR is unaffected. 25328986 2014