IGF1R, insulin like growth factor 1 receptor, 3480

N. diseases: 422; N. variants: 24
Disease: Malignant neoplasm of breast ×
Source: BEFREE ×
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2016347
rs2016347
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.020 GeneticVariation BEFREE Pregnancy Hypertension and a Commonly Inherited IGF1R Variant (rs2016347) Reduce Breast Cancer Risk by Enhancing Mammary Gland Involution. 31687025 2019
dbSNP: rs2016347
rs2016347
Entrez Id: 3480
Gene Symbol: IGF1R
IGF1R
CUI: C0006142
Disease:
Malignant neoplasm of breast 		0.020 GeneticVariation BEFREE Study findings indicate that the T allele of IGF1R variant rs2016347 is associated with a significant reduction in breast cancer risk in women with a history of preeclampsia, most marked for HR+ breast cancer and in women with AFB < 30. 28822014 2017