|
rs1064794050
|
IGF2;MIR483;INS-IGF2
|
Russell-Silver syndrome
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1114167321
|
IGF2;MIR483;INS-IGF2
|
Russell-Silver syndrome
|
ACG |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs869320620
|
IGF2;MIR483;INS-IGF2
|
GROWTH RESTRICTION, SEVERE, WITH DISTINCTIVE FACIES
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Diabetes Mellitus, Insulin-Dependent
|
C |
0.810 |
GeneticVariation |
GWASDB |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Diabetes Mellitus, Insulin-Dependent
|
C |
0.810 |
GeneticVariation |
GWASCAT |
A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.
|
17632545 |
2007 |
|
rs3741208
|
IGF2;IGF2-AS;INS-IGF2
|
Diabetes Mellitus, Insulin-Dependent
|
T |
0.800 |
GeneticVariation |
GWASCAT |
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
|
17554260 |
2007 |
|
rs3741208
|
IGF2;IGF2-AS;INS-IGF2
|
Diabetes Mellitus, Insulin-Dependent
|
T |
0.800 |
GeneticVariation |
GWASDB |
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.
|
17554260 |
2007 |
|
rs984257990
|
IGF2;MIR483;INS-IGF2
|
Malignant neoplasm of breast
|
|
0.010 |
GeneticVariation |
BEFREE |
The purposes of this study were to analyse the genotype of TGF-beta1 at T29C and TGF-beta1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer.
|
18827819 |
2008 |
|
rs984257990
|
IGF2;MIR483;INS-IGF2
|
Breast Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
The purposes of this study were to analyse the genotype of TGF-beta1 at T29C and TGF-beta1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer.
|
18827819 |
2008 |
|
rs984257990
|
IGF2;MIR483;INS-IGF2
|
Mammary Neoplasms
|
|
0.010 |
GeneticVariation |
BEFREE |
The purposes of this study were to analyse the genotype of TGF-beta1 at T29C and TGF-beta1 phenotype in breast tumours, and to evaluate their associations with IGFs and clinical characteristics of breast cancer.
|
18827819 |
2008 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Diabetes Mellitus, Insulin-Dependent
|
G |
0.810 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
|
21829393 |
2011 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Autoantibody measurement
|
G |
0.700 |
GeneticVariation |
GWASDB |
Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.
|
21829393 |
2011 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Multiple Sclerosis
|
|
0.700 |
GeneticVariation |
GWASDB |
Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.
|
22190364 |
2011 |
|
rs4320932
|
IGF2;INS-IGF2
|
Malignant neoplasm of ovary
|
|
0.020 |
GeneticVariation |
BEFREE |
In the combined set of studies, rs4320932 was associated with a 13% decreased risk of ovarian cancer per copy of the minor allele carried (95% confidence interval 0.81-0.93, P-trend=7.4 × 10(-5)).
|
21422097 |
2011 |
|
rs4320932
|
IGF2;INS-IGF2
|
Carcinoma, Ovarian Epithelial
|
|
0.020 |
GeneticVariation |
BEFREE |
In the combined set of studies, rs4320932 was associated with a 13% decreased risk of ovarian cancer per copy of the minor allele carried (95% confidence interval 0.81-0.93, P-trend=7.4 × 10(-5)).
|
21422097 |
2011 |
|
rs4320932
|
IGF2;INS-IGF2
|
ovarian neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
In the combined set of studies, rs4320932 was associated with a 13% decreased risk of ovarian cancer per copy of the minor allele carried (95% confidence interval 0.81-0.93, P-trend=7.4 × 10(-5)).
|
21422097 |
2011 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Malignant neoplasm of endometrium
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs1004446
|
IGF2;IGF2-AS;INS-IGF2
|
Endometrial Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs3741211
|
IGF2;IGF2-AS;INS-IGF2
|
Malignant neoplasm of endometrium
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs3741211
|
IGF2;IGF2-AS;INS-IGF2
|
Endometrial Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed an inverse association with IGFII rs3741211 and endometrial cancer risk (OR=0.79 (95% CI: 0.63, 0.99)) and IGFII rs1004446 and endometrial cancer risk (OR=0.80 (95% CI: 0.68, 0.94)).
|
21078522 |
2011 |
|
rs680
|
IGF2;INS-IGF2
|
Malignant tumor of colon
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association of four insulin-related pathway gene polymorphisms in insulin-like growth factor-1 (IGF-I) (CA)( n ) repeat, insulin-like growth factor-2 (IGF-II) (rs680), insulin-like growth factor-binding protein-3 (IGFBP-3) (rs2854744), and adiponectin (APM1 rs1501299) with colon cancer risk, as well as relationships with circulating IGF-I, IGF-II, IGFBP-3, and C-peptide in a population-based study.
|
22565227 |
2012 |
|
rs680
|
IGF2;INS-IGF2
|
Colon Carcinoma
|
|
0.010 |
GeneticVariation |
BEFREE |
We evaluated the association of four insulin-related pathway gene polymorphisms in insulin-like growth factor-1 (IGF-I) (CA)( n ) repeat, insulin-like growth factor-2 (IGF-II) (rs680), insulin-like growth factor-binding protein-3 (IGFBP-3) (rs2854744), and adiponectin (APM1 rs1501299) with colon cancer risk, as well as relationships with circulating IGF-I, IGF-II, IGFBP-3, and C-peptide in a population-based study.
|
22565227 |
2012 |
|
rs4320932
|
IGF2;INS-IGF2
|
Malignant neoplasm of ovary
|
|
0.020 |
GeneticVariation |
BEFREE |
The C allele of rs4320932, previously associated with decreased risk of ovarian cancer development, was here associated with significantly elevated risks of relapse (Ptrend = 0.0002) and death (Ptrend = 0.0006), remaining significant in multivariate analyses.
|
23677070 |
2013 |
|
rs4320932
|
IGF2;INS-IGF2
|
Carcinoma, Ovarian Epithelial
|
|
0.020 |
GeneticVariation |
BEFREE |
The C allele of rs4320932, previously associated with decreased risk of ovarian cancer development, was here associated with significantly elevated risks of relapse (Ptrend = 0.0002) and death (Ptrend = 0.0006), remaining significant in multivariate analyses.
|
23677070 |
2013 |
|
rs4320932
|
IGF2;INS-IGF2
|
ovarian neoplasm
|
|
0.020 |
GeneticVariation |
BEFREE |
The C allele of rs4320932, previously associated with decreased risk of ovarian cancer development, was here associated with significantly elevated risks of relapse (Ptrend = 0.0002) and death (Ptrend = 0.0006), remaining significant in multivariate analyses.
|
23677070 |
2013 |