rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
A family with Alzheimer disease and strokes associated with A713T mutation of the APP gene.
15365148
2004
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease.
15201367
2004
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
An Iranian family with Alzheimer's disease caused by a novel APP mutation (Thr714Ala ).
12034808
2002
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
In vitro studies of amyloid beta-protein fibril assembly and toxicity provide clues to the aetiology of Flemish variant (Ala692-->Gly) Alzheimer's disease.
11311152
2001
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation.
11528419
2001
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Early-onset Alzheimer disease caused by a new mutation (V717L) in the amyloid precursor protein gene.
10867787
2000
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.
11063718
2000
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein.
10677483
2000
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Identification of a novel aspartic protease (Asp 2) as beta-secretase.
10656250
1999
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-->Gly mutation.
9754958
1998
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).
9328472
1997
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease.
8577393
1995
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations.
8267572
1993
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production.
1465129
1992
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Linkage and mutational analysis of familial Alzheimer disease kindreds for the APP gene region.
1415269
1992
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid.
1302033
1992
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Presenile dementia and cerebral haemorrhage linked to a mutation at codon 692 of the beta-amyloid precursor protein gene.
1303239
1992
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
More missense in amyloid gene.
1303275
1992
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Mis-sense mutation Val----Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease.
1678058
1991
rs63750643
×
Entrez Id:
351
Gene Symbol:
APP
APP
Alzheimer's Disease
0.700
GeneticVariation
UNIPROT
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
1671712
1991