APP, amyloid beta precursor protein, 351

N. diseases: 485; N. variants: 114
Disease: Alzheimer Disease, Late Onset ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs63750847
rs63750847
Entrez Id: 351
Gene Symbol: APP
APP
CUI: C0494463
Disease:
Alzheimer Disease, Late Onset 		0.030 GeneticVariation BEFREE The A673T variant is extremely rare in US cohorts and does not play a substantial role in risk for AD in this population. 25531812 2015
dbSNP: rs63750847
rs63750847
Entrez Id: 351
Gene Symbol: APP
APP
CUI: C0494463
Disease:
Alzheimer Disease, Late Onset 		0.030 GeneticVariation BEFREE A coding gene variant A673T (rs63750847) in the APP gene has recently been recognized as a protective variant of late-onset Alzheimer's Disease in a large Icelandic population and has been observed recurrently in populations from Nordic countries. 26239177 2015
dbSNP: rs63750847
rs63750847
Entrez Id: 351
Gene Symbol: APP
APP
CUI: C0494463
Disease:
Alzheimer Disease, Late Onset 		0.030 GeneticVariation BEFREE Investigation of an amyloid precursor protein protective mutation (A673T) in a North American case-control sample of late-onset Alzheimer's disease. 24529499 2014