IL1RN, interleukin 1 receptor antagonist, 3557

N. diseases: 701; N. variants: 52
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10171849
rs10171849
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0200633
Disease:
Neutrophil count (procedure)
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs121913161
rs121913161
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C2748507
Disease:
INTERLEUKIN 1 RECEPTOR ANTAGONIST DEFICIENCY
T 0.700 CausalMutation CLINVAR
dbSNP: rs121913162
rs121913162
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C2748507
Disease:
INTERLEUKIN 1 RECEPTOR ANTAGONIST DEFICIENCY
T 0.700 CausalMutation CLINVAR
dbSNP: rs128964
rs128964
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C3815172
Disease:
Interleukin 1 Beta Measurement
0.700 GeneticVariation GWASCAT GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. 30206230 2018
dbSNP: rs13404928
rs13404928
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C3815172
Disease:
Interleukin 1 Beta Measurement
0.700 GeneticVariation GWASCAT GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. 30206230 2018
dbSNP: rs1380437028
rs1380437028
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0002736
Disease:
Amyotrophic Lateral Sclerosis
0.010 GeneticVariation BEFREE Temporal patterns of cytokine and apoptosis-related gene expression in spinal cords of the G93A-SOD1 mouse model of amyotrophic lateral sclerosis. 12124437 2002
dbSNP: rs1457547311
rs1457547311
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0085695
Disease:
Chronic gastritis
0.010 GeneticVariation BEFREE Multiple logistic regression analysis (log-additive, dominant, and recessive models) have not showed association of the genotype frequencies for the SNP TNFB + 252A/G with risk of CG or GC. 22327782 2012
dbSNP: rs1457547311
rs1457547311
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0699791
Disease:
Stomach Carcinoma
0.010 GeneticVariation BEFREE Multiple logistic regression analysis (log-additive, dominant, and recessive models) have not showed association of the genotype frequencies for the SNP TNFB + 252A/G with risk of CG or GC. 22327782 2012
dbSNP: rs1457547311
rs1457547311
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0024623
Disease:
Malignant neoplasm of stomach
0.010 GeneticVariation BEFREE Multiple logistic regression analysis (log-additive, dominant, and recessive models) have not showed association of the genotype frequencies for the SNP TNFB + 252A/G with risk of CG or GC. 22327782 2012
dbSNP: rs1457547311
rs1457547311
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0679408
Disease:
Lesion of stomach
0.010 GeneticVariation BEFREE Polymorphisms TNF-A-308G/A, IL-8-251A/T, TNF-B + 252A/G and TLR4 + 1196C/T were not associated with risk of any gastric lesion. 23086128 2013
dbSNP: rs1630153
rs1630153
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C3815172
Disease:
Interleukin 1 Beta Measurement
0.700 GeneticVariation GWASCAT GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. 30206230 2018
dbSNP: rs1688075
rs1688075
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C1384600
Disease:
Systemic onset juvenile chronic arthritis
0.010 GeneticVariation BEFREE Meta-analysis of the genotypes from both stages showed that three IL1 ligand cluster SNPs (rs6712572, rs2071374 and rs1688075) and one IL1 receptor cluster SNP (rs12712122) show evidence of significant association with sJIA. 18418395 2008
dbSNP: rs1794067
rs1794067
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C3815172
Disease:
Interleukin 1 Beta Measurement
0.700 GeneticVariation GWASCAT GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. 30206230 2018
dbSNP: rs1794068
rs1794068
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C3815172
Disease:
Interleukin 1 Beta Measurement
0.700 GeneticVariation GWASCAT GWAS for Interleukin-1β levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation. 30206230 2018
dbSNP: rs1794068
rs1794068
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0036341
Disease:
Schizophrenia
0.010 GeneticVariation BEFREE Neither combined nor stratified analyses found any association of the rs1800587 (IL1A gene; T-889C) or rs1794068 (IL1RA Gene; IL1RN_86 bp; T/C) with schizophrenia susceptibility. 20347268 2010
dbSNP: rs201638660
rs201638660
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0410422
Disease:
Chronic multifocal osteomyelitis
0.010 GeneticVariation BEFREE In one patient with chronic multifocal osteomyelitis a heterozygous missense variant: c.281G>T (p.Cys94Phe) was detected. 22032624 2012
dbSNP: rs2029582
rs2029582
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0200633
Disease:
Neutrophil count (procedure)
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2029582
rs2029582
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0200641
Disease:
Blood basophil count (lab test)
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2029582
rs2029582
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0200638
Disease:
Eosinophil count procedure
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2029582
rs2029582
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0857490
Disease:
Granulocyte count
C 0.700 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252 2016
dbSNP: rs2234663
rs2234663
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0042900
Disease:
Vitiligo
0.010 GeneticVariation BEFREE More case-control studies on interleukin 1 receptor antagonist rs2234663 polymorphism and gene expression from different ethnic populations are required to explore the impact of interleukin 1 receptor antagonist in vitiligo susceptibility. 29620037 2018
dbSNP: rs2234663
rs2234663
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0151779
Disease:
Cutaneous Melanoma
0.010 GeneticVariation BEFREE The present study investigated whether a variable number tandem repeat (VNTR) polymorphism of interleukin-1 receptor antagonist (IL-1RA) gene (<i>IL-1RN</i>) located in intron 2 (rs2234663) is associated with cutaneous melanoma. 31788049 2019
dbSNP: rs2234663
rs2234663
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0018213
Disease:
Graves Disease
0.010 GeneticVariation BEFREE The present study was aimed to determine the genetic associations between polymorphisms of IL-1β gene promoter region (-511 T>C) (rs16944), exon 5 (+3954 C>T) (rs1143634) and IL-1RN gene VNTR (rs2234663) polymorphism in patients with GD in ethnic Kashmiri population. 29454070 2018
dbSNP: rs2234663
rs2234663
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0029443
Disease:
Osteomyelitis
0.010 GeneticVariation BEFREE We investigated the association of IL1RNVNTR (rs2234663) and IL1B-511C > T (rs16944) polymorphisms with osteomyelitis development in patients operated on because of bone trauma. 28682145 2017
dbSNP: rs2234663
rs2234663
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
CUI: C0031069
Disease:
Familial Mediterranean Fever
0.010 GeneticVariation BEFREE The IL-4 rs79071878 polymorphism, was associated whereas the IL-1Ra rs2234663 polymorphism was not associated with FMF risk in the Turkish population. 26861613 2016