IL4, interleukin 4, 3565

N. diseases: 996; N. variants: 23
Disease: Carcinoma of lung ×
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2243250
rs2243250
Entrez Id: 3565
Gene Symbol: IL4
IL4
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE In our findings, rs2243250 was associated with a decreased lung cancer risk under the log-additive model (odds ratio, OR = 0.71, 95% confidence interval, CI = 0.51-0.97, p = 0.030), and the G/G genotype of rs2227284 conferred a negative effect; the risk of lung cancer under the codominant (OR = 0.19, 95% CI = 0.04-0.87, p = 0.040) and recessive models (OR = 0.20, 95% CI = 0.04-0.88, p = 0.012) after adjusted by age. 30729744 2019
dbSNP: rs2243250
rs2243250
Entrez Id: 3565
Gene Symbol: IL4
IL4
CUI: C0684249
Disease:
Carcinoma of lung 		0.020 GeneticVariation BEFREE The present study aimed at evaluating the contribution of IL-4 promoter T-1099G (rs2243248), C-589T (rs2243250), C-33T (rs2070874) genetic polymorphisms to the risk of lung cancer in Taiwan. 26504066 2015