CXCL10, C-X-C motif chemokine ligand 10, 3627

N. diseases: 631; N. variants: 9
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs11548618
rs11548618
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C2985280
Disease:
Blood Protein Measurement
A 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0202202
Disease:
Protein measurement
C 0.700 GeneticVariation GWASCAT Cross-genetic determination of maternal and neonatal immune mediators during pregnancy. 30134952 2018
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0019196
Disease:
Hepatitis C
0.030 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0019196
Disease:
Hepatitis C
0.030 GeneticVariation BEFREE The homozygosity for the minor alleles CXCL9 rs10336 (T), CXCL10 rs3921 (G), and CXCL11 rs4619915 (A) is associated with the higher likelihood of significant liver fibrosis in HIV-infected patients coinfected with HCV-GT1. 25559603 2015
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0019196
Disease:
Hepatitis C
0.030 GeneticVariation BEFREE The presence of homozygous for the minor allele of CXCL9 rs10336, CXCL10 rs3921 and CXCL11 rs4619915 was related to higher likelihoods of achieving the HCV clearance after pegIFNα/ribavirin therapy in HIV infected patients coinfected with HCV GT1/4. 25218243 2014
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C1861453
Disease:
Pseudohyperkalemia Cardiff
0.010 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0524910
Disease:
Hepatitis C, Chronic
0.010 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs56061981
rs56061981
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0041327
Disease:
Tuberculosis, Pulmonary
0.010 GeneticVariation BEFREE Regulatory role of CCL5 (rs2280789) and CXCL10 (rs56061981) gene polymorphisms on intracellular CCL5 and CXCL10 expression in pulmonary tuberculosis. 28336310 2018
dbSNP: rs56061981
rs56061981
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0024117
Disease:
Chronic Obstructive Airway Disease
0.010 GeneticVariation BEFREE Stratified analysis of smoking status and biomass with SNPs supported rs56061981 may interact with biomass and smoking thus modulate COPD susceptibility and rs56216945 was apparently associated with the severity of pulmonary function of COPD patients. 29285564 2018
dbSNP: rs56061981
rs56061981
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0041296
Disease:
Tuberculosis
0.010 GeneticVariation BEFREE In -135G/A (rs56061981) polymorphism, PTB patients with GG genotype showed a significantly decreased expression of CD3+ CXCL10+ and CD3+ CD4+ CXCL10+ T cells compared to A allele carrier (GA+AA) under unstimulated, CFA induced and M. tuberculosis infected cultures (P<0.05). 28336310 2018
dbSNP: rs8878
rs8878
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0524910
Disease:
Hepatitis C, Chronic
0.010 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs8878
rs8878
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C1861453
Disease:
Pseudohyperkalemia Cardiff
0.010 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs8878
rs8878
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0019196
Disease:
Hepatitis C
0.010 GeneticVariation BEFREE Here we recruited chronic hepatitis C (CHC) patients to perform an association study between three single nucleotide polymorphisms (SNPs) (CXCR2 rs1126579, CXCL10 rs8878 and CXCL10 rs3921) and HCV infection outcomes and treatment responses among a Chinese population, using primarily a TaqMan assay. 29948377 2018
dbSNP: rs4256246
rs4256246
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0036341
Disease:
Schizophrenia
0.010 GeneticVariation BEFREE Significant SNPxDiagnosis interactions were identified for eight serum proteins including Factor-VII[rs555212], Alpha-1-Antitrypsin[rs11846959], Interferon-Gamma Induced Protein 10[rs4256246] and von-Willebrand-Factor[rs12829220] in the control group; Chromogranin-A[rs9658644], Cystatin-C[rs2424577] and Vitamin K-Dependent Protein S[rs6123] in the schizophrenia group; Interleukin-6 receptor[rs7553796] in both the control and schizophrenia groups. 28974776 2017
dbSNP: rs56061981
rs56061981
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0019693
Disease:
HIV Infections
0.010 GeneticVariation BEFREE In MDR analyses revealed that the CXCL10 rs56061981 and CCL22 rs4359426 combination was the best model, with 57% accuracy (P = 0.008) for predicting susceptibility to HIV infection. 28358741 2017
dbSNP: rs4508917
rs4508917
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0006142
Disease:
Malignant neoplasm of breast
0.010 GeneticVariation BEFREE Different association was also observed between rs4508917</span> and CXCL10 levels in patients with BC and healthy subjects. 27002757 2016
dbSNP: rs4508917
rs4508917
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0678222
Disease:
Breast Carcinoma
0.010 GeneticVariation BEFREE Different association was also observed between rs4508917</span> and CXCL10 levels in patients with BC and healthy subjects. 27002757 2016
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C3854222
Disease:
Human immunodeficiency virus (HIV) II infection category B1
0.010 GeneticVariation BEFREE The homozygosity for the minor alleles CXCL9 rs10336 (T), CXCL10 rs3921 (G), and CXCL11 rs4619915 (A) is associated with the higher likelihood of significant liver fibrosis in HIV-infected patients coinfected with HCV-GT1. 25559603 2015
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0239946
Disease:
Fibrosis, Liver
0.010 GeneticVariation BEFREE The homozygosity for the minor alleles CXCL9 rs10336 (T), CXCL10 rs3921 (G), and CXCL11 rs4619915 (A) is associated with the higher likelihood of significant liver fibrosis in HIV-infected patients coinfected with HCV-GT1. 25559603 2015
dbSNP: rs4859584
rs4859584
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0011311
Disease:
Dengue Fever
0.010 GeneticVariation BEFREE We genotyped 14 common variants of these candidate genes in 176 patients infected with dengue. rs4859584 and rs8878 (CXCL10) were significantly associated with vascular permeability of dengue infection (P<0.05); while variants of CXCL11 showed moderate significance of association (P=0.0527). 25858769 2015
dbSNP: rs8878
rs8878
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0003873
Disease:
Rheumatoid Arthritis
0.010 GeneticVariation BEFREE The aim of this study was to examine the associations between polymorphisms in the CXCL9 (rs3733236 G>A) and CXCL10 (rs8878 A>G) genes and RA. 25702175 2015
dbSNP: rs1126858
rs1126858
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0016053
Disease:
Fibromyalgia
0.010 GeneticVariation BEFREE Two nonsense mutations, W32X in C11orf40 and Q100X in ZNF77 among 150 FMS trios had a significantly elevated frequency of transmission to affected probands (p = 0.026 and p = 0.032, respectively) and were present in a subset of 13% and 11% of FMS patients, respectively. 23762283 2013
dbSNP: rs3921
rs3921
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0376545
Disease:
Hematologic Neoplasms
0.010 GeneticVariation BEFREE This study retrospectively examined the impact of a single nucleotide variation (rs3921, +1642C>G) in the CXCL10 gene on transplant outcomes in a cohort of 652 patients who underwent unrelated HLA-matched bone marrow transplantation (BMT) for hematologic malignancies. 23291247 2013
dbSNP: rs4508917
rs4508917
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0024534
Disease:
Malaria, Cerebral
0.010 GeneticVariation BEFREE Following extensive bioinformatics analyses, two reported single nucleotide polymorphisms in the CXCL10 promoter (-135G>A [rs56061981] and -1447A>G [rs4508917]) were identified among 66 CM and 69 non-CM Indian patients using PCR-restriction fragment length polymorphism assay. 24349056 2013
dbSNP: rs56061981
rs56061981
Entrez Id: 419;3627
Gene Symbol: ART3;CXCL10
ART3;CXCL10
CUI: C0024534
Disease:
Malaria, Cerebral
0.010 GeneticVariation BEFREE Following extensive bioinformatics analyses, two reported single nucleotide polymorphisms in the CXCL10 promoter (-135G>A [rs56061981] and -1447A>G [rs4508917]) were identified among 66 CM and 69 non-CM Indian patients using PCR-restriction fragment length polymorphism assay. 24349056 2013