IRF4, interferon regulatory factor 4, 3662

N. diseases: 203; N. variants: 10
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASCAT A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. 24292274 2014
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASDB A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. 24292274 2014
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASCAT Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASDB Genome-wide association study identifies multiple risk loci for chronic lymphocytic leukemia. 23770605 2013
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASDB Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. 22700719 2012
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASCAT Common variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemia. 22700719 2012
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
0.840 GeneticVariation BEFREE A recent genome wide association study of chronic lymphocytic leukaemia (CLL) provided evidence that common variation at 2q13 (rs17483466), 2q37.1 (rs13397985), 6p25.3 (rs872071), 11q24.1 (rs735665), 15q23 (rs7176508) and 19q13.32 (rs11083846) affects CLL risk. 20553269 2010
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
0.840 GeneticVariation BEFREE Common single nucleotide polymorphisms (SNPs) at 2q13 (rs17483466), 2q37.1 (rs13397985), 2q37.3 (rs757978), 6p25.3 (rs872071), 8q24.21 (rs2456449), 11q24.1 (rs735665), 15q21.3 (rs7169431), 15q23 (rs7176508), 16q24.1 (rs305061), and 19q13.32 (rs11083846) have been shown to confer a modest but significant increase in CLL risk. 20855867 2010
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
0.840 GeneticVariation BEFREE We have recently shown that the IRF4 variant rs872071 influences CLL risk. 19804451 2010
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
0.840 GeneticVariation BEFREE We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASCAT We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008
dbSNP: rs872071
rs872071
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0023434
Disease:
Chronic Lymphocytic Leukemia
G 0.840 GeneticVariation GWASDB We identified six previously unreported CLL risk loci at 2q13 (rs17483466; P = 2.36 x 10(-10)), 2q37.1 (rs13397985, SP140; P = 5.40 x 10(-10)), 6p25.3 (rs872071, IRF4; P = 1.91 x 10(-20)), 11q24.1 (rs735665; P = 3.78 x 10(-12)), 15q23 (rs7176508; P = 4.54 x 10(-12)) and 19q13.32 (rs11083846, PRKD2; P = 3.96 x 10(-9)). 18758461 2008
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0015396
Disease:
Eye Color
0.800 GeneticVariation GWASCAT Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort. 30166351 2018
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
C 0.800 GeneticVariation GWASCAT Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. 23548203 2013
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
C 0.800 GeneticVariation GWASDB Genome-wide association studies identify several new loci associated with pigmentation traits and skin cancer risk in European Americans. 23548203 2013
dbSNP: rs1050976
rs1050976
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0007570
Disease:
Celiac Disease
0.800 GeneticVariation GWASCAT Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. 22057235 2011
dbSNP: rs1050976
rs1050976
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0007570
Disease:
Celiac Disease
0.800 GeneticVariation GWASDB Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. 22057235 2011
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0038868
Disease:
Progressive supranuclear palsy
0.800 GeneticVariation GWASDB Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0038868
Disease:
Progressive supranuclear palsy
0.800 GeneticVariation GWASCAT Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy. 21685912 2011
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0015396
Disease:
Eye Color
T 0.800 GeneticVariation GWASDB Web-based, participant-driven studies yield novel genetic associations for common traits. 20585627 2010
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
T 0.800 GeneticVariation GWASCAT Web-based, participant-driven studies yield novel genetic associations for common traits. 20585627 2010
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0015396
Disease:
Eye Color
T 0.800 GeneticVariation GWASCAT Web-based, participant-driven studies yield novel genetic associations for common traits. 20585627 2010
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
T 0.800 GeneticVariation GWASDB Web-based, participant-driven studies yield novel genetic associations for common traits. 20585627 2010
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
T 0.800 GeneticVariation GWASDB After adjustment for rs12203592, the association between rs1540771 and hair color was not significant (p = 0.52). 18483556 2008
dbSNP: rs12203592
rs12203592
Entrez Id: 3662
Gene Symbol: IRF4
IRF4
CUI: C0018498
Disease:
Hair Color
T 0.800 GeneticVariation GWASCAT After adjustment for rs12203592, the association between rs1540771 and hair color was not significant (p = 0.52). 18483556 2008